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B-CALMplex

product on market Capsule Natural Rhythm Safety: 97/100
97/100

This product looks safe

  • Vitamin B3: 55mg is 1.6× the Tolerable Upper Intake Level (35mg)
  • 82% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains a complex of B vitamins that support cellular energy metabolism and neurological function. Research provides strong evidence for the roles of these vitamins in maintaining cognitive health and metabolic processes. The overall evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B3: 55mg is 1.6× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for B-CALMplex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetable Capsule(s)
Serving Size
90
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

55 mg (3667% DV)
45.8× RDA — above typical dose 76 studies (A:0, B:33)
55 mg (3235% DV)
42.3× RDA — above typical dose 13 studies (A:0, B:1)
55 mg (275% DV)
Exceeds UL by 1.6× (UL: 35 mg) 196 studies (A:5, B:63)
55 mg (2750% DV)
42.3× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
200 mcg (50% DV)
Within RDA (0.5× RDA) 226 studies (A:10, B:105)
12 mcg (200% DV)
5.0× RDA — above typical dose 139 studies (A:1, B:44)
100 mcg (33% DV)
3.3× RDA — above typical dose 27 studies (A:0, B:11)
55 mg (550% DV)
11.0× RDA — above typical dose 2 studies — no high-quality reviews
55 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
55 mg
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
55 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose Vegetable Cellulose vegetarian Leucine
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take 1 capsule daily with a meal, or as directed by your healthcare practitioner.

Warnings & Precautions

Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.

Keep out of reach of children.

Formulation Notes

Restore your rhythm Support your immune system

Fight Stress & Anxiety B-CALMplex is a premium stress B complex formula that helps you manage stress, support your immune system function, and reduce irritability. Find Calm & Balance B-CALMplex contains an optimal balance of essential B vitamins, which help promote cardiovascular health and overall cellular renewal. B vitamins help decrease stress, anxiety, and fatigue while helping to boost your energy and mental focus.

Made in the USA

Pure. Max absorption. Easy on stomach.

A premium stress B complex formula

To support stress management, proper nerve function, and relaxation

Vegetarian

Gluten free

Non-GMO

Color of this product may vary due to color variations of the natural ingredients.

Additional Information

GMP Good Manufacturing Practice Quality Product

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU7 64804 31744 2
DSLD Entry Date2022-08-23
Product TypeOther Combinations
FormCapsule
BrandNatural Rhythm
DSLD ID271231
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.