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Coenzyme B Complex

product on market Capsule Innate Response Formulas Safety: 95/100
95/100

This product looks safe

  • Niacin: 42.5mg is 1.2× the Tolerable Upper Intake Level (35mg)
  • Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • 86% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins, including thiamine, riboflavin, and niacin, which are essential for cellular energy metabolism and neurological function. There is strong research evidence supporting the role of these nutrients in maintaining metabolic health. The ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 42.5mg is 1.2× the Tolerable Upper Intake Level (35mg)

Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Coenzyme B Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
86%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

90 mg (7500% DV)
75.0× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (833% DV)
8.3× RDA — above typical dose 76 studies (A:0, B:33)
17 mg (1308% DV)
13.1× RDA — above typical dose 13 studies (A:0, B:1)
3 mg (231% DV)
2.3× RDA — within safe limits 13 studies (A:0, B:1)
42.5 mg NE (266% DV)
Exceeds UL by 1.2× (UL: 35 mg) 196 studies (A:5, B:63)
7.5 mg NE (47% DV)
Within RDA (0.5× RDA) 196 studies (A:5, B:63)
20 mg (1176% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
340 mcg DFE (85% DV)
Exceeds UL by 340.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
500 mcg (20833% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
100 mg (18% DV)
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
40 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Cellulose Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 1 capsule daily, or as directed by your healthcare practitioner. May be taken anytime throughout the day.

Formulation Notes

Supports healthy energy levels

In this INNATE Response product each vitamin is paired with an ideal whole food using our unique process to deliver guaranteed potency and the benefit of health-promoting compounds present in the whole food itself.

Satisfaction guaranteed or your money back. Learn more at: www.innateresponse.com

Vegetarian

Glyphosate Residue Free detoxproject.org No Magnesium Stearate Mgst

Additional Information

Please Recycle Vis medicatrix naturae

At INNATE Response we share your belief that nothing is more important than supporting your body's innate ability to heal. To that end, we develop nutrient-rich supplements.

Certified B Corporation Glyphosate Residue Free detoxproject.org

To learn more about our seals, please visit innateresponse.com/standards.

Metadata

Product Details

UPC / SKU0 51494 43000 2
DSLD Entry Date2022-07-21
Product TypeOther Combinations
FormCapsule
BrandInnate Response Formulas
DSLD ID268024
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.