Better B
97/100
This product looks safe
- Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
- 75% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Label Data
1 Capsule(s)
Serving Size
90
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Supplement Facts — Evidence Check
25 mg
(1667% DV)
📊 20.8× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
10 mg
(588% DV)
📊 7.7× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
50 mg
(250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
10 mg
(500% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
400 mcg
(100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg)
📚 225 studies (Tier A: 10, B: 105)
100 mcg
(1667% DV)
📊 41.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
330 mcg
(110% DV)
📊 11.0× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
100 mg
(1000% DV)
📊 20.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
50 mg
✅ Within RDA (0.1× RDA of 550 mg)
📚 36 studies (Tier A: 1, B: 7)
25 mg
📊 Market median: 550.0mg (217 products)
📚 29 studies (Tier A: 0, B: 5)
45 mg
📊 Market median: 500.0mg (9 products)
Intrinsic factor
20 mg
Other Ingredients
Rice Flour
Gelatin
Corn Starch
L-Leucine
Glyceryl Behenate
Medium Chain Triglyceride
Silica
Label Claims — Verification
❓
Nutrient
❓
All Other
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (47% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
⚠️ Warnings & Precautions
Pregnant and/or lactating women should consult their physician prior to use.
Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.
Keep out of reach of children.
🧪 Formulation Notes
Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)
Gluten free
High potency bioactive B-Vitamins
Additional Information
Directions: One capsule three times daily, with food, or as directed by a health care professional.
Sold only for dispensing by a licensed health care professional.
GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 111
Product Details
UPC / SKU
3 51821 01036 6
DSLD Entry Date
2022-04-11
Product Type
Other Combinations
Form
Capsule
DSLD ID
261404
Data Updated
2026-04-11
Research Evidence
100
Research Sources
56
Avg Quality Score
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
B
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
B
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
B
Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
B
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
B
Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
B
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
B
The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
B
Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
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