One Daily Essential
97/100
This product looks safe
- Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
- 67% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Tablet(s)
Serving Size
100
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Supplement Facts — Evidence Check
Vitamin A
900 mcg
(100% DV)
Vitamin C
60 mg
(67% DV)
10 mcg
(50% DV)
✅ Within RDA (0.7× RDA of 0.015 mg)
📚 604 studies (Tier A: 16, B: 251)
13.5 mg
(90% DV)
✅ Within RDA (0.9× RDA of 15 mg)
📚 177 studies (Tier A: 3, B: 90)
1.5 mg
(125% DV)
✅ 1.2× RDA — within safe limits
📚 76 studies (Tier A: 0, B: 33)
1.7 mg
(131% DV)
✅ 1.3× RDA — within safe limits
📚 12 studies (Tier A: 0, B: 1)
20 mg
(125% DV)
✅ 1.4× RDA — within safe limits
📚 193 studies (Tier A: 5, B: 63)
2 mg
(118% DV)
✅ 1.5× RDA — within safe limits
📚 113 studies (Tier A: 3, B: 35)
667 mcg DFE
(167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
6 mcg
(250% DV)
✅ 2.5× RDA — within safe limits
📚 138 studies (Tier A: 1, B: 44)
10 mg
(200% DV)
✅ 2.0× RDA — within safe limits
📚 1 studies — no high-quality reviews
Calcium
93 mg
(7% DV)
Other Ingredients
Cellulose
Starch
Gelatin
Stearic Acid
Croscarmellose Sodium
Artificial Colors
Magnesium Silicate
Magnesium Stearate
Maltodextrin
PEG
Polyvinyl alcohol
Silicon Dioxide
Titanium Dioxide
Label Claims — Verification
❓
Nutrient
❓
All Other
All Other (99% of products)
Structure/Function (76% of products)
Nutrient (58% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Directions: As a dietary supplement, adults take one (1) tablet daily with any meal or as directed by your healthcare provider. Do not exceed recommended dosage.
⚠️ Warnings & Precautions
Do not exceed recommended dosage.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
🧪 Formulation Notes
Gluten free
No added Yeast or Artificial Flavors. Gluten free.
Additional Information
Compare vs. One a day essential
Individual results may vary.
Store at room temperature.
Guaranteed quality Laboratory tested
Product Details
UPC / SKU
7 40985 27303 6
DSLD Entry Date
2022-01-22
Product Type
Other Combinations
Form
Tablet or Pill
Brand
21st Century
DSLD ID
258543
Data Updated
2026-04-11
Research Evidence
337
Research Sources
54
Avg Quality Score
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A
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A
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A
Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
A
Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
A
Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
A
Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
A
Food fortification with multiple micronutrients: impact on health outcomes in general population
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