🟢 98/100

This product looks safe

  • Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • 47% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Liquid Softgel(s) Serving Size
30 Servings
Other Combinations Product Type
47% Evidence Coverage

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Fat
1 Gram(s) (2% DV)
Total Carbohydrates
1 Gram(s) (1% DV)
Protein
1 Gram(s)
10 mg (63% DV)
✅ Within RDA (0.7× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 10mg UL 35mg
5 mg (294% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
340 mcg DFE (85% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 340.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 340mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
15 mg (300% DV)
✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 15mg
850 mg
📊 Market median: 1000.0mg (212 products) 📚 12 studies (Tier A: 0, B: 3)
This product: 850mg
Medium Chain Triglyceride Oil
500 mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 300mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 270mg
250 mg
📊 Market median: 500.0mg (357 products) 📚 1 studies — no high-quality reviews
This product: 250mg
📊 Market median: 650.0mg (87 products) 📚 1 studies — no high-quality reviews
This product: 150mg
75 mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 75mg UL 400mg
BioPerine Complex
3 mg

Other Ingredients

Gelatin purified Water Glycerin Beeswax Soy Lecithin Annatto Turmeric Titanium Dioxide Silicon Dioxide Sodium Copper Chlorophyllin Maltodextrin Dicalcium Phosphate Mannitol

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Women (not pregnant or lactating) Adult Female (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: (Adult) Take two (2) Liquid Soft-Gels twice a day, with meals and a full glass (8 oz) of water. If caffeine keeps you up at night, do not take this product in the evening since it contains (natural) caffeine.

⚠️ Warnings & Precautions

Usage Warnings: Do not use if safety seal is broken. This product contains natural caffeine and may affect blood sugar.

Check with your doctor before using this product if you are using medication or have any medical conditions, including, but not limited to, heart disease, high blood pressure, an iron deficiency, a liver disorder or develop symptoms of liver trouble (such as abdominal pain, dark urine or jaundice). Do not use if you may become pregnant, are pregnant on nursing.

Do not exceed recommended daily intake.

Not intended for use by persons under 18. Keep out of reach of children.

Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Contains: Dairy, soy, tree nuts (coconut, palm kernel)

🧪 Formulation Notes

VO2 Max Performance Fat Burner is a multi-pronged female-centric formula that delivers powerful performance boost by supporting that female body in four key ways: Boost Themogenesis & Metabolism: EGCG from Green Tea Extract+ Caffeine enhance metabolism and help burn calories.

This thermogenic combination—while not literally "melting" fat off the body-supports increased thermogenesis and fat burning (fat oxidation).

Optimize Endurance: This powerful formula features KSM-66 Ashwagandha Extract, which is prized for its ability to combat the negative effects of stress, and increase physical endurance in female athletes. KSM-66 is combined with Maca Root plus Schisandra Berry Extract which is a valuable adaptogen used traditionally to support stamina and vitality. Combat fatigue: In addition to the fatigue-fighting effects of KSM-66 and Natural Caffeine, this product also delivers MCT Oil along with a specialized blend of B Vitamins to support cellular energy production.

What is VO2 Max? VO2 Max is a clinical measure of physical endurance and indicates how well the body manages oxygen consumption during strenuous exercise. The higher the VO2 Max is, the greater the fitness of the body. KSM-66 has been shown to significantly improve VO2 Max in female athletes.

What makes us different: Liquid Soft-Gels - The nutrients in these easy-to-swallow Liquid Soft-Gels are released fast.

Patented BioPerine - Our special BioPerine Complex enhances the bioavailability, absorption and potency of many nutrients.

Specialized for women

Thermogenic boost Optimize endurance Increase metabolism Combat fatigue

No preservatives added.

Additional Information

Based on a study which included both male and female subjects.

Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft-Gels provide an optimum delivery system.

Pass Quality Tested Guaranteed Quality Assurance - Irwin Naturals is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency. Global Responsibility - Over the years we have donated to organizations that support the environment and the health of our children.

Store in a cool, dry place.

Questions: Contact Consumer Affairs 1-800-297-3273 Weekdays 8:00 AM to 5:00 PM (PST) 100+ Highly specialized products: www.IrwinNaturals.com

Full Disclosure Ingredient Panel

Product Details

UPC / SKU 7 10363 59868 6
DSLD Entry Date 2021-10-22
Product Type Other Combinations
Form Softgel Capsule
DSLD ID 256641
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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