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Centrum Energy & Vitality

product on market Capsule Centrum Safety: 98/100
98/100

This product looks safe

  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 71% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins, including thiamine, riboflavin, and niacin, which are supported by strong evidence for their role in cellular energy metabolism. These nutrients facilitate the conversion of carbohydrates into usable energy. The overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Centrum Energy & Vitality
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
25
Servings
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
1.2 mg (100% DV)
Within RDA (1.0× RDA) 76 studies (A:0, B:33)
1.3 mg (100% DV)
Within RDA (1.0× RDA) 13 studies (A:0, B:1)
4 mg (25% DV)
Within RDA (0.3× RDA) 196 studies (A:5, B:63)
1.7 mg (100% DV)
1.3× RDA — within safe limits 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
24 mcg (1000% DV)
10.0× RDA — above typical dose 139 studies (A:1, B:44)
30 mcg (100% DV)
Within RDA (1.0× RDA) 27 studies (A:0, B:11)
5 mg (100% DV)
Within RDA (1.0× RDA) 2 studies — no high-quality reviews
105 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)
15 mg
Market median: 180.0mg (239 products) 49 studies (A:1, B:19)
Organic Botanical Blend
200 mg

Other Ingredients

organic Rice Flour Hypromellose Contains less than 2% of:
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults: Take two (2) capsules daily with food. Do not exceed suggested use.

Warnings & Precautions

Not formulated for use in children.

As with any supplement, if you are pregnant, nursing, or taking medication, consult your doctor before use.

Keep out of reach of children.

If taking other supplements, read label, since supplements may contain the same ingredient.

Do not use if inner foil seal under cap is torn or missing.

Formulation Notes

Hollistic cellular energy support

CoQ10 and B vitamins

Purposefully crafted to support your mind & body

Powered by B vitamins and CoQ10 for natural energy support. Our B-complex helps convert the foods you eat to the fuel you need. We've included an organic botanical blend of maca root, pomegranate, and ginseng.

Proudly manufactured in a GMP facility.

Non-GMO and vegetarian.

Non-GMO and vegetarian. No synthetic colors, gelatin, dairy, soy, or nuts.

Additional Information

Store at room temperature, 15-30 degrees C (59-86 degrees F). Protect from heat, light and moisture.

New! gsk

Metadata

Product Details

UPC / SKU3 05734 98550 1
DSLD Entry Date2021-07-27
Product TypeOther Combinations
FormCapsule
BrandCentrum
DSLD ID251343
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.