Centrum Energy & Vitality

product on market Capsule Centrum 🟢 Safety: 98/100
Brand: Centrum
🟢 98/100

This product looks safe

  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 71% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
25 Servings
Other Combinations Product Type
71% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
1.2 mg (100% DV)
✅ Within RDA (1.0× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 1.2mg
1.3 mg (100% DV)
✅ Within RDA (1.0× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 1.3mg
4 mg (25% DV)
✅ Within RDA (0.3× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 4mg UL 35mg
1.7 mg (100% DV)
✅ 1.3× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 1.7mg UL 100mg
400 mcg DFE (100% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 400.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 400mg UL 1.0mg
24 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.024mg
30 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.03mg
5 mg (100% DV)
✅ Within RDA (1.0× RDA of 5 mg) 📚 1 studies — no high-quality reviews
RDA 5mg This product: 5mg
105 mg (25% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 105mg
50 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 50mg UL 1200mg
15 mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 15mg UL 400mg
Organic Botanical Blend
200 mg

Other Ingredients

organic Rice Flour Hypromellose Contains less than 2% of:

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: Adults: Take two (2) capsules daily with food. Do not exceed suggested use.

⚠️ Warnings & Precautions

Not formulated for use in children.

As with any supplement, if you are pregnant, nursing, or taking medication, consult your doctor before use.

Keep out of reach of children.

If taking other supplements, read label, since supplements may contain the same ingredient.

Do not use if inner foil seal under cap is torn or missing.

🧪 Formulation Notes

Hollistic cellular energy support

CoQ10 and B vitamins

Purposefully crafted to support your mind & body

Powered by B vitamins and CoQ10 for natural energy support. Our B-complex helps convert the foods you eat to the fuel you need. We've included an organic botanical blend of maca root, pomegranate, and ginseng.

Proudly manufactured in a GMP facility.

Non-GMO and vegetarian.

Non-GMO and vegetarian. No synthetic colors, gelatin, dairy, soy, or nuts.

Additional Information

Store at room temperature, 15-30 degrees C (59-86 degrees F). Protect from heat, light and moisture.

New! gsk

Product Details

UPC / SKU 3 05734 98550 1
DSLD Entry Date 2021-07-27
Product Type Other Combinations
Form Capsule
Brand Centrum
DSLD ID 251343
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
PubMed Cochrane
View all evidence for Thiamine →

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