B-Complex
93/100
This product looks safe
- Niacin: 75mg is 2.1× the Tolerable Upper Intake Level (35mg)
- Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
- 82% of ingredients have research evidence
D
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 75mg is 2.1× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Supplement Facts — Evidence Check
87.5 mg
(7292% DV)
📊 72.9× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
25 mg
(1923% DV)
📊 19.2× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
75 mg
(469% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.1× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
25 mg
(1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
666 mcg DFE
(167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 666.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
400 mcg
(16667% DV)
📊 166.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
300 mcg
(1000% DV)
📊 10.0× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
100 mg
(2000% DV)
📊 20.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
20 mg
(4% DV)
📊 Market median: 125.0mg (294 products)
📚 36 studies (Tier A: 1, B: 7)
25 mg
📊 Market median: 500.0mg (9 products)
18 mg
📊 15.0× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
Other Ingredients
Vegetable Cellulose
Rice Flour
Leucine
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (47% of products)
Target Groups
Vegetarian
Adult (18 - 50 Years)
Gluten Free
Dairy Free
Product Information
📋 Directions for Use
Suggested Use: Take 1 capsule as a dietary supplement, preferably with a meal, or as directed by your health practitioner.
⚠️ Warnings & Precautions
Caution: If you are pregnant, nursing, or taking any medications, consult your health practitioner before use.
Discontinue use and consult your health practitioner if any adverse reactions occur.
Keep out of reach of children.
Use only if safety seal is intact.
🧪 Formulation Notes
Vegetarian
Gluten free Non-GMO
Free Of: Milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, yeast and gluten. Free of ingredients derived from GMOs.
Active Essentials with Quatrefolic
Additional Information
Store in a cool, dry place.
BPA free
Exclusive Professional Formulas
Product Details
UPC / SKU
8 53959 00445 8
DSLD Entry Date
2021-05-22
Product Type
Other Combinations
Form
Capsule
DSLD ID
249165
Data Updated
2026-04-11
Research Evidence
100
Research Sources
56
Avg Quality Score
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
B
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
B
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
B
Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
B
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
B
Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
B
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
B
The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
B
Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
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