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Ester-C Effervescent 1000 mg Natural Orange

product on market Powder American Health Safety: 98/100
98/100

This product looks safe

  • Folate: 20mg is 20.0× the Tolerable Upper Intake Level (1.0mg)
  • 55% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C, thiamine, and riboflavin are essential nutrients supported by strong evidence for maintaining immune function and cellular energy metabolism. These ingredients contribute to overall metabolic health, though the overall evidence coverage for this specific formulation is limited. The product maintains a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 20mg is 20.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Ester-C Effervescent 1000 mg Natural Orange
Open Full PDF View on NIH DSLD →
Details

Label Data

10 Gram(s)
Serving Size
21
Servings
Other Combinations
Product Type
55%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
25 Calorie(s)
Total Carbohydrates
6 Gram(s) (2% DV)
Vitamin C
1026 mg (1140% DV)
0.38 mg (32% DV)
Within RDA (0.3× RDA) 76 studies (A:0, B:33)
0.43 mg (33% DV)
Within RDA (0.3× RDA) 13 studies (A:0, B:1)
5 mg (31% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
20 mcg DFE (5% DV)
Exceeds UL by 20.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
25 mcg (1042% DV)
10.4× RDA — above typical dose 139 studies (A:1, B:44)
2.5 mg (50% DV)
Within RDA (0.5× RDA) 2 studies — no high-quality reviews
Calcium
150 mg (12% DV)
150 mg (12% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:3)
60 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
2 mg (18% DV)
Within RDA (0.2× RDA) 263 studies (A:6, B:134)
0.5 mg (22% DV)
Within RDA (0.2× RDA) 9 studies — no high-quality reviews
5 mcg (14% DV)
Within RDA (0.1× RDA) 199 studies (A:1, B:55)
90 mg (4% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Sodium
100 mg (4% DV)
Potassium
280 mg (6% DV)
Antioxidant Health Proprietary Blend
58 mg

Other Ingredients

Fructose Maltodextrin Malic Acid Citric Acid natural Orange flavor Silica Beta-Carotene Vegetable Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Once a day is all you need.

Just take one packet daily with 4-6 fl. oz. of water and you are good to go!

Directions: For adults, pour packet into 4-6 fl. oz. of water once daily. Stir or shake.

Take once a day!

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if packet is torn or open.

Formulation Notes

The Ester-C Difference: Clinically studied to stay in white blood cells longer than regular vitamin c Unique formula with 24/7 immune support

Ester-C Effervescent Vitamin C packets offer 24-hour immune support in a delicious, natural orange flavored formula.

Unique Ester-C increases levels of Vitamin C in the body-- getting into white blood cells (an important part of you immune system), and staying there longer than regular vitamin C. One serving daily of 1000 mg of Ester-C delivers 24-hour immune support and potent antioxidant activity... 365 days a year.

Taken once a day, Ester-C has your immune health covered. It supports circulation, is beneficial to joints and connective tissues, and is involved in collagen formation, which forms the basis of healthy skin. As a potent antioxidant, it helps fight free radicals. Free radicals can cause oxidative stress, which may lead to premature aging of metabolic cells. Ester-C also aids in the nutritional absorption of iron and works with other nutrients to promote overall health.

Along with essential vitamins, such as B-6 and B-12 to support energy metabolism and vital electrolytes to aid in metabolic hydration, Ester-C Effervescent Formula has your immune support covered.

Along with essential vitamins, such as B-6 and B-12 to support energy metabolism and vital electrolytes to aid in metabolic hydration, Ester-C Effervescent Formula has got you covered.

No gluten, no yeast, no wheat, no dairy, no lactose, no soy, no egg, no grapefruit, no artificial sweetener, no peanuts, no tree nuts, no fish.

Natural orange flavor, beta-carotene added for color.

Non-GMO.

Vegetarian/vegan

One packet provides as much vitamin C as 10 oranges

Plus electrolytes Unique Vitamin C formula B vitamins to support energy metabolism

24-hour immune support

Vegan

Non-GMO No Artificial sweeteners

Additional Information

Ester-C The better vitamin C

Now more than ever, trust your immune health to Ester-C.

Store at room temperature.

^ Food is the best source of nutrients, but supplements can help. Based on USDA.gov nutrient database for 1 large, raw orange.

Metadata

Product Details

DSLD Entry Date2021-04-22
Product TypeOther Combinations
FormPowder
DSLD ID248855
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.