🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
60 Servings
Botanical with Nutrients Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

27 mg (5% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 27mg UL 3500mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 300mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 125mg
📊 Market median: 300.0mg (122 products) 📚 22 studies (Tier A: 0, B: 7)
This product: 100mg
📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)
This product: 0.1mg

Other Ingredients

Vegetarian Capsule Microcrystalline Cellulose Croscarmellose Sodium Magnesium Stearate Silica

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Usage: 2 capsules 1-2 times per day or as directed by a health professional.

⚠️ Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

🧪 Formulation Notes

Three Brains is a line of supplements designed to support the critical relationship between our head, heart, and gut. Together, these three "brains" influence our cognition and support a healthy mind.

Serene Mind contains unique combination of herbal extracts used to help relieve symptoms of everyday stress, enhance physical performance, and support cognitive function.

It is also used as a supportive therapy for the maintenance of healthy glucose levels already within the normal range and helps promote healthy liver function. Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

Support for stress-related fatigue

Serene Mind provides powerful support for the adrenal glands during periods of occasional emotional or physical stress and demands. It synergistically combines several adaptognes with choline and green tea. Key ingredients key benefits Sensoril Ashwagandha an adaptogen that calms the mind and regulates cortisol Panax ginseng an adaptogen that supports mood, energy, and focus. Rhodiola an adaptogen that balances everyday stress, reduces mental fatigue, and promotes attention Choline helps the adrenal glands respond to stress Sunphenon green tea supports a calm but alert mind

Product of Canada

Additional Information

isura Non-GMO - Mass spec Documentation - Lab tested

For freshness, store in a cool, dry place.

Recyclable container and label.

Purity & Potency Guaranteed

“Nutrients from whole foods, exercise, and supplements are effective, non-invasive ways to support the ‘three brains’ interaction – optimize cognition and support a healthy mind.” – Karen Jensen, ND A bold new innovation in healthy mind support!

Serene Mind is an excellent stand-alone product, but can be combined with 3 Brains Total for comprehensive and optimal three-brain support.

Gut Directly engaged with the world Head Observing the world Heart Reaching out to the world

Product Details

UPC / SKU 0 68958 03057 9
DSLD Entry Date 2021-04-22
Product Type Botanical with Nutrients
Form Capsule
DSLD ID 247490
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
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