🟢 96/100

This product looks safe

  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 90% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Veg Capsule(s) Serving Size
45 Servings
Other Combinations Product Type
90% Evidence Coverage

Supplement Facts — Evidence Check

2 mg (118% DV)
✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 2mg UL 100mg
667 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 667mg UL 1.0mg
60 mcg (2500% DV)
📊 25.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.06mg
225 mcg (150% DV)
✅ 1.5× RDA — within safe limits 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.225mg UL 1.1mg
25 mg (227% DV)
✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 25mg UL 40mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
1 mg (111% DV)
✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1mg UL 10mg
1 Gram(s)
📊 Market median: 500.0mg (223 products) 📚 22 studies (Tier A: 0, B: 1)
This product: 1mg
Guggul (Commiphora mukul) (gum resin) standardized extract
75 mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 50mg

Other Ingredients

Cellulose Cellulose powder Magnesium Stearate Silica

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 2 capsules daily, preferably in divided doses with food.

⚠️ Warnings & Precautions

Caution: For adults only.

Not recommended for pregnant/nursing women. Consult physician if taking medication, or have a medical condition including known ulcer.

May cause mild transient GI upset. Discontinue use if GI symptoms persist.

Individuals with thyroid disorders or those taking warfarin, thyroid medications, L-dopa, SNRIs, MAO inhibitors, or other mood altering medications should seek the advice of a physician before consuming this product.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

To report a serious adverse event, or for product information, contact 1-800-234-8686

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

This product is a complete nutritional supplement for the support of a healthy thyroid gland.

We have combined Iodine and Tyrosine, the two constituents necessary for the synthesis of thyroid secretions. The minerals Selenium, Zinc and Copper have been added as cofactors needed for normal thyroid function. In addition, this product has the Ayurvedic herbal extracts from Guggul and Ashwagandha to complement its nutritional support components.

Natural color variation may occur in this product.

Provides key components for the support of healthy thyroid hormones

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Non-GMO

Additional Information

Douglas Cooper Co. "Trace Minerals Make the Difference" Since 1950

Product Details

DSLD Entry Date 2021-05-22
Product Type Other Combinations
Form Capsule
DSLD ID 247426
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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