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Age Defying

product on market Other (e.g. tea bag) Rx Select Beauty Safety: 87/100
87/100

This product is generally safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 69% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains a complex of B vitamins, including thiamine, riboflavin, and niacin, which support cellular energy metabolism and skin health. There is strong research evidence for the role of these nutrients in maintaining systemic physiological functions. The overall evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Age Defying
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
60
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (667% DV)
8.3× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (588% DV)
7.7× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
15 mg (750% DV)
11.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
200 mcg (50% DV)
Within RDA (0.5× RDA) 226 studies (A:10, B:105)
100 mcg (1667% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
5000 mcg (1667% DV)
166.7× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
100 mg (10% DV)
85 mg (9% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
30 mg (200% DV)
2.7× RDA — within safe limits 263 studies (A:6, B:134)
5 mg (250% DV)
2.2× RDA — within safe limits 9 studies — no high-quality reviews
Proprietary Blend
645 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Coating Croscarmellose Sodium Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 caplet daily with a meal as a dietary supplement or as directed by a healthcare professional.

Warnings & Precautions

Keep out of reach of children.

Do not use if seal is broken.

Formulation Notes

Advanced hair formula Younger looking skin Stronger, healthier nails

Hair, Skin & Nails Renewal Formula with OptiMSM & Biotin

Additional Information

Protect from heat, light and moisture. Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 35046 09102 6
DSLD Entry Date2020-11-21
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandRx Select Beauty
DSLD ID240172
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.