🟢 87/100

This product is generally safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 69% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
69% Evidence Coverage

Supplement Facts — Evidence Check

10 mg (667% DV)
📊 8.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 10mg
10 mg (588% DV)
📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 10mg
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
15 mg (750% DV)
📊 11.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 15mg UL 100mg
200 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.2mg UL 1.0mg
100 mcg (1667% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
5000 mcg (1667% DV)
📊 166.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 5.0mg
50 mg (500% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
Calcium
100 mg (10% DV)
85 mg (9% DV)
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 85mg UL 4000mg
30 mg (200% DV)
✅ 2.7× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 30mg UL 40mg
5 mg (250% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
Proprietary Blend
645 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Coating Croscarmellose Sodium Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Take 1 caplet daily with a meal as a dietary supplement or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Keep out of reach of children.

Do not use if seal is broken.

🧪 Formulation Notes

Advanced hair formula Younger looking skin Stronger, healthier nails

Hair, Skin & Nails Renewal Formula with OptiMSM & Biotin

Additional Information

Protect from heat, light and moisture. Store in a cool, dry place.

Product Details

UPC / SKU 0 35046 09102 6
DSLD Entry Date 2020-11-21
Product Type Other Combinations
Form Other (e.g. tea bag)
DSLD ID 240172
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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