Advanced Brain Nutrients

product on market Capsule Higher Nature 🟢 Safety: 95/100
Brand: Higher Nature
🟢 95/100

This product looks safe

  • Niacin: 200mg is 5.7× the Tolerable Upper Intake Level (35mg)
  • 62% of ingredients have research evidence
C Label Compliance Grade

Product Label

Label for Advanced Brain Nutrients
📄 Open Full PDF View on NIH DSLD →
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Safety Alerts

⚠️ Niacin: 200mg is 5.7× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
Other Combinations Product Type
62% Evidence Coverage

Supplement Facts — Evidence Check

200 mg NE (125% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 5.7× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 200mg UL 35mg
100 mcg (50% DV)
✅ Within RDA (0.2× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.1mg UL 1.0mg
20 mcg (800% DV)
📊 8.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.02mg
200 mg (3333% DV)
📊 40.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 200mg
Phosphatidyl Serine
30 mg
260 mg
✅ Within RDA (0.5× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 260mg UL 3500mg
200 mg
📊 Market median: 500.0mg (143 products)
This product: 200mg
100 mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 100mg

Other Ingredients

Omega Choline Bitartrate Capsule Vitamin B5 L-Arginine Pyroglutamate Acetyl L-Carnitine HCl Phosphatidyl Serine-rich Lecithin Silicon Dioxide Magnesium Stearate Vitamin B3 Folic Acid Vitamin B12

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Children 4 or More Years of Age Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Adults take 2 capsules once or twice a day (children 8 and over 1 capsule a day) at least 30 minutes before meals. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Storage: Store in a cool, dry place out of reach of children.

🧪 Formulation Notes

Free From: Artificial colours, flavourings, preservatives, dairy products, gluten, lactose, salt, starch, sugar, wheat, yeast.

Mind health Nootropic formula Fuel for the brain Supports mental performance

Vegetarian and vegan

Vitamin B5 contributes to normal mental performance and metabolism of some neurotransmitters. Vitamins B3 and B12 contribute to normal psychological function and the reduction of tiredness and fatigue

Additional Information

NRV = Nutrient Reference Value

This product has not been tested on animals.

Storage: Store in a cool, dry place out of reach of children.

Product Details

UPC / SKU 5 031013 104572
DSLD Entry Date 2020-06-24
Product Type Other Combinations
Form Capsule
Brand Higher Nature
DSLD ID 228278
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
PubMed DOI
View all evidence for Niacin →

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