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B-Complex 50

product on market Capsule GNC Safety: 93/100
93/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 82% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This blend contains B vitamins that support energy metabolism and neurological function. There is strong clinical evidence for the role of thiamine, folate, and B6 in cellular health. The high safety score indicates a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-Complex 50
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
50 mcg (2083% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
50 mcg (167% DV)
1.7× RDA — within safe limits 27 studies (A:0, B:11)
50 mcg (1000% DV)
Market median: 9.0mg (620 products) 2 studies — no high-quality reviews
20 mg (4% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
50 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Gelatin Corn Starch Calcium Silicate Mono & Diglycerides Magnesium Stearate Rice Bran Powder Stearic Acid Silicon Dioxide Brewer's Yeast Soy Lecithin Alfalfa leaf powder Watercress herb powder Parsley herb powder
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one capsule daily.

Warnings & Precautions

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery. Niacin may cause a temporary flushing reaction. Inform your physician of this product's biotin content before any lab test.

Keep out of reach of children.

Contains: Wheat and soybeans.

Formulation Notes

Metabolism & energy production Immune & nervous system functions Healthy brain, skin, hair and nails

Potencies verified by GNC procedures #5103 and #5118. Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

No sugar, no artificial colors, no artificial flavors, no dairy.

Additional Information

Store in a cool, dry place.

250-day supply

Metadata

Product Details

UPC / SKU0 48107 17717 1
DSLD Entry Date2020-06-24
Product TypeOther Combinations
FormCapsule
BrandGNC
DSLD ID227969
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.