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Co-Enzyme B Complex

product on market Capsule Ecological Formulas Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 82% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins that support energy metabolism and neurological function. There is strong evidence for the role of thiamine, riboflavin, and folate in cellular processes. The ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Co-Enzyme B Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
50
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

60 mg (4000% DV)
50.0× RDA — above typical dose 76 studies (A:0, B:33)
60 mg (3550% DV)
46.2× RDA — above typical dose 13 studies (A:0, B:1)
30 mg (150% DV)
2.1× RDA — within safe limits 196 studies (A:5, B:63)
67 mg (3350% DV)
51.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
250 mcg (4150% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
288 mg (2900% DV)
57.6× RDA — above typical dose 2 studies — no high-quality reviews
Within RDA (0.5× RDA) 38 studies (A:1, B:7)
150 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
30 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Gelatin Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS Take two capsules daily, or as recommended by a physician.

Formulation Notes

Yeast Free

The nutrients contained within these capsules are the purest, U.S.P. reagent grade vitamins available and contain no diluents, preservatives, chemical additives, or other allergenic ingredients. Contains no yeast, soy, or wheat.

Additional Information

EXP1112

CO-ENZYME B COMPLEX is a scientifically-designed dietary product containing a completely balanced and well-absorbed B Vitamin Formula. Biotin, folic acid, and cyanocobalamin are derived from bacterial sources.

ECOLOGICAL FORMULAS

11051947

Metadata

Product Details

DSLD Entry Date2013-06-25
Product TypeOther Combinations
FormCapsule
BrandEcological Formulas
DSLD ID22320
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.