B-Supreme
96/100
This product looks safe
- Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
- 80% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Label Data
1 Capsule(s)
Serving Size
Other Combinations
Product Type
80%
Evidence Coverage
Supplement Facts — Evidence Check
100 mg
(6667% DV)
📊 83.3× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
50 mg
(2941% DV)
📊 38.5× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
50 mg
(250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
50 mg
(2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
200 mcg
(50% DV)
✅ Within RDA (0.5× RDA of 0.4 mg)
📚 225 studies (Tier A: 10, B: 105)
250 mcg
(4167% DV)
📊 104.2× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
2 mg
(667% DV)
📊 66.7× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
100 mg
(1000% DV)
📊 20.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
200 mg
✅ Within RDA (0.4× RDA of 550 mg)
📚 36 studies (Tier A: 1, B: 7)
200 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Other Ingredients
Microcrystalline Cellulose
Silicon Dioxide
Vegetable Stearate
Label Claims — Verification
❓
All Other
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (47% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Recommended Use: As a dietary supplement, take one capsule per day with a meal, or as directed by your health care practitioner.
⚠️ Warnings & Precautions
KEEP OUT OF REACH OF CHILDREN.
🧪 Formulation Notes
Does not contain gluten.
Additional Information
Notice: Color, size or shape may appear different between lots.
BSP060-1
For Professional Use Only
Guaranteed GMP COMPLIANT Products
Manufactured in an NSF GMP Registered Facility
STORE IN A COOL, DRY PLACE.
Product Details
UPC / SKU
8 79452 00119 0
DSLD Entry Date
2013-08-23
Product Type
Other Combinations
Form
Capsule
Brand
Designs for Health
DSLD ID
22273
Data Updated
2026-04-11
Research Evidence
100
Research Sources
56
Avg Quality Score
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
B
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
B
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
B
Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
B
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
B
Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
B
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
B
The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
B
Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
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