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Mega B-100

product on market Capsule Vitamin World Safety: 87/100
87/100

This product is generally safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 75% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The B-vitamin complex, including thiamine, riboflavin, and folic acid, is supported by strong evidence for maintaining energy metabolism and neurological function. These ingredients play critical roles in cellular health and red blood cell formation. Research generally indicates a high safety profile for these nutrients when taken within recommended daily limits.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Mega B-100
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (6667% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
100 mg (5882% DV)
76.9× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (500% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5000% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg (200% DV)
2.0× RDA — within safe limits 226 studies (A:10, B:105)
100 mcg (1667% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
1000 mcg (333% DV)
33.3× RDA — above typical dose 27 studies (A:0, B:11)
100 mg (1000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
100 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
100 mcg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Proprietary Blend
7.5 mg

Other Ingredients

Gelatin Crospovidone Vegetable Cellulose Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: For adults, take one (1) caplet daily, preferably with a meal.

Warnings & Precautions

WARNING: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

No Artificial Color or Flavor, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Additional Information

Vitamin World products are subject to critically stringent quality assurance analysis. Our state-of-the-art laboratory, manufacturing and packaging facilities insure the highest quality nutritional supplements money can buy. Your health & safety are our first priority!

QA QUALITY ASSURED

Store at room temperature.

PROD. #10283 B11280 06D

Get healthy.

Supports Energy Metabolism* Supports Heart Health*

Metadata

Product Details

UPC / SKU7 66443 10283 0
DSLD Entry Date2013-04-25
Product TypeOther Combinations
FormCapsule
DSLD ID20912
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.