🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 47% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
47% Evidence Coverage

Supplement Facts — Evidence Check

1.5 mg (7.5% DV)
✅ Within RDA (0.1× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 1.5mg UL 35mg
500 mcg (8333.5% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
600 mg
📊 Market median: 495.0mg (70 products)
Median 495.0mg This product: 600mg
250 mg
📊 Market median: 983.0mg (16 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 250mg
Yohimbe bark extract
100 mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 75mg UL 3500mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 50mg
Bacopa extract
45 mg
40 mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 40mg UL 400mg
DMAE
37.5 mg
White Willow bark extract
30 mg
📊 Market median: 500.0mg (223 products) 📚 22 studies (Tier A: 0, B: 1)
This product: 25mg
Piperine
3 mg
Vinpocetine
2.5 mg
50 mcg
📊 Market median: 0.15mg (41 products)
Median 0.15mg This product: 0.05mg

Other Ingredients

Stearic Acid Dicalcium Phosphate Microcrystalline Cellulose Croscarmellose Sodium Magnesium Stearate Silicon Dioxide Pharmaceutical Glaze

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take one tablet daily. Pills can be split in half at first to judge it's strength, which we recommend. Not recommended to take more than two pills in one day. Slowly build up the dose if you take more than one.

⚠️ Warnings & Precautions

Warning: Not intended for persons under the age of 18.

Do not use if pregnant or nursing. Consult a health care professional prior to consumption if you have any pre-existing medical conditions or any prescription medication.

Do not consume with any caffeine or stimulants. Improper use of this product will not improve results and is potentially hazardous to a person's health. Use only as directed.

Keep out of reach of children.

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 7 48252 28689 5
DSLD Entry Date 2019-10-23
Product Type Other Combinations
Form Tablet or Pill
Brand Addrena
DSLD ID 206821
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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