Home/ Supplements/ Chondroitin/ Glucosamine & Chondroitin Sulfate (CSA)

Glucosamine & Chondroitin Sulfate (CSA)

product on market Other (e.g. tea bag) Glucoflex Safety: 97/100
97/100

This product looks safe

  • Magnesium: 400mg is 1.1× the Tolerable Upper Intake Level (350mg)
  • 58% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The formula contains essential minerals and vitamins, including calcium and magnesium, which support bone health and metabolic function. Research provides strong evidence for the role of vitamins D and K in calcium absorption and skeletal maintenance. However, overall evidence coverage for this specific ingredient combination remains limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 400mg is 1.1× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Glucosamine & Chondroitin Sulfate (CSA)
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
10
Servings
Other Combinations
Product Type
58%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
100 mg (167% DV)
200 IU (50% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
20 mcg (25% DV)
Within RDA (0.2× RDA) 275 studies (A:9, B:175)
Calcium
800 mg (80% DV)
400 mg (100% DV)
Exceeds UL by 1.1× (UL: 350 mg) 316 studies (A:8, B:159)
15 mg (100% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
5 mg (250% DV)
2.2× RDA — within safe limits 9 studies — no high-quality reviews
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
1.5 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Herbal Co-Factors Blend
500 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Silica Vegetable Magnesium Stearate Film Coat
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two caplets 3 times daily preferably with meals as a dietary supplement or as directed by a healthcare professional.

Warnings & Precautions

Contains shellfish (shrimp, crab, lobster, and prawns)

Caution: Do not take this product if you are allergic to shellfish.

Keep out of reach of children

Safety Sealed - Individually sealed for your protection. Do not use if foil-back blister pack has been tampered with.

Formulation Notes

Plus Advanced Herbal Co-Factors

Comprehensive Bone and Joint Support Supplement containing an advanced Herbal Co-Factors blend with vitamins and minerals

Contains shellfish (shrimp, crab, lobster, and prawns)

Additional Information

Advanced Bone and Joint Support Supplement

Store in a cool, dry place. Protect from heat, light and moisture.

ITEM # N4032 60740012

Made in the U.S.A.

Metadata

Product Details

UPC / SKU0 35046 14032 8
DSLD Entry Date2018-08-31
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGlucoflex
DSLD ID180633
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
48
Avg Quality
21
Rct
10
Meta Analysis
2
Clinical Trial
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
C Update on the role of pharmaceutical-grade chondroitin sulfate in the symptomatic management of knee osteoarthritis
Meta Analysis Aging clinical and experimental research 2019 PubMed DOI
C Evaluation of efficacy and safety of glucosamine sulfate, chondroitin sulfate, and their combination regimen in the management of knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Inflammopharmacology 2024 PubMed DOI
C Does incorporating collagen and chondroitin sulfate matrix in implant surfaces enhance osseointegration? A systematic review and meta-analysis
Meta Analysis International journal of oral and maxillofacial surgery 2018 PubMed DOI
C Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials
Meta Analysis Rheumatology international 2018 PubMed DOI
View all evidence for Chondroitin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.