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Glucosamine & Chondroitin Sulfate

product on market Other (e.g. tea bag) Glucoflex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Glucosamine HCl and chondroitin sulfate are researched for their role in supporting joint cartilage and reducing degenerative symptoms. Evidence for their efficacy in treating joint discomfort is generally considered moderate to limited across clinical studies. These ingredients are typically well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine & Chondroitin Sulfate
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Magnesium Stearate Silica Film Coat
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one caplet twice daily, preferably with meals, as a dietary supplement, or as directed by a healthcare professional.

2 caplets daily

Warnings & Precautions

Keep out of reach of children.

Do not use if seal is broken.

Caution: Do not take this product if you are allergic to shellfish.

Contains shellfish.

Formulation Notes

Contains shellfish.

Additional Information

All natural, bone and joint support supplement designed to help support the bone building process.

Store in a cool, dry place. Protect from heat, light and moisture.

Safety sealed-Individually sealed for your protection.

Joint support formula

Triple strength

Item# 4420 TC# 62031202

Made in the USA.

Convenience formula

Metadata

Product Details

UPC / SKU0 35046 04420 6
DSLD Entry Date2017-02-24
Product TypeNon-Nutrient/Non-Botanical
FormOther (e.g. tea bag)
BrandGlucoflex
DSLD ID71089
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
48
Avg Quality
21
Rct
10
Meta Analysis
2
Clinical Trial
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
C Update on the role of pharmaceutical-grade chondroitin sulfate in the symptomatic management of knee osteoarthritis
Meta Analysis Aging clinical and experimental research 2019 PubMed DOI
C Evaluation of efficacy and safety of glucosamine sulfate, chondroitin sulfate, and their combination regimen in the management of knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Inflammopharmacology 2024 PubMed DOI
C Does incorporating collagen and chondroitin sulfate matrix in implant surfaces enhance osseointegration? A systematic review and meta-analysis
Meta Analysis International journal of oral and maxillofacial surgery 2018 PubMed DOI
C Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials
Meta Analysis Rheumatology international 2018 PubMed DOI
View all evidence for Chondroitin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.