Coenzyme B Food Complex by New Chapter — Ingredients, Evidence & Safety

🟢 98/100

This product looks safe

Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)
73% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)

Label Data

1 Tablet(s) Serving Size

Botanical with Nutrients Product Type

73% Evidence Coverage

Supplement Facts — Evidence Check

Thiamin

5 mg (333% DV)

📊 4.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 5mg

Riboflavin

9 mg (529% DV)

📊 6.9× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 9mg

Niacin

45 mg (225% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 45mg UL 35mg

Vitamin B6

9 mg (450% DV)

📊 6.9× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 9mg UL 100mg

Folate

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

120 mcg (2000% DV)

📊 50.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.12mg

Biotin

300 mcg (100% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

45 mg (450% DV)

📊 9.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 45mg

Stress and Energy Support Blend

150 mg

Cardio Support Blend

60 mg

Immune Support Blend

56.2 mg

organic Turmeric (rhizome) powder

5.4 mg

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)

This product: 5.4mg

Ginger (rhizome) hydroethanolic extract

3.2 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 3.2mg

organic Turmeric (rhizome) supercritical extract

1.6 mg

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)

This product: 1.6mg

organic Ginger (rhizome) supercritical extract

0.8 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 0.8mg

Other Ingredients

Culture Media organic Gum Acacia Silicon Dioxide Lac Resin Maltodextrin Carnauba Wax Magnesium Carbonate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Kosher Organic Gluten Free

Product Information

📋 Directions for Use

Suggested use: One tablet daily. Can be taken anytime, even on an empty stomach.

Improved formula, now one-per-day dose Can be taken on an empty stomach

⚠️ Warnings & Precautions

Caution: As with any dietary or herbal supplement, you should advise your healthcare professional of the use of this product.

If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare professional prior to using this product.

Contains: Fermented soy and fermented wheat (as food source for Saccharomyces cerevisiae).

🧪 Formulation Notes

Non-GMO project verified.

Gluten free; 100% vegetarian; no artificial flavors or colors.

Made with organic vegetables & herbs

Whole-food cultured B vitamins for energy & nervous system support

Contains: Fermented soy and fermented wheat (as food source for Saccharomyces cerevisiae).

The wheat has been processed to allow this food to meet the Food and Drug Administration (FDA) requirements for gluten-free foods.

Certified Organic by International Certification Services, Inc., Medina, ND, USA

Additional Information

Probiotic-cultured.

Whole-food complexed.

Get the Whole Truth! Sign up for our e-newsletter at newchapter.com/newsletter Please refer to newchapter.com for more information about this product and its benefits.

Please recycle this bottle after use. Made in the USA

0350-E01

ICS Certified Organic

New formula

The New Chapter Money-Back Guarantee: We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details.

Product Details

DSLD Entry Date 2018-06-25

Product Type Botanical with Nutrients

Form Tablet or Pill

Brand New Chapter

DSLD ID 178370

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →