🟢 97/100

This product looks safe

  • Niacin: 60mg is 1.7× the Tolerable Upper Intake Level (35mg)
  • 38% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 60mg is 1.7× the Tolerable Upper Intake Level (35mg)

Label Data

11.66 fl. Oz. Serving Size
12 Servings
Other Combinations Product Type
38% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
60 mg (300% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.7× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 60mg UL 35mg
1 mg (50% DV)
✅ Within RDA (0.8× RDA of 1.3 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 1mg UL 100mg
500 mcg (125% DV)
✅ 1.2× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.5mg UL 1.0mg
70 mcg (1167% DV)
📊 29.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.07mg
Sodium
125 mg (5% DV)
6 Gram(s)
📊 Market median: 2000.0mg (275 products)
Median 2000.0mg This product: 6mg
CarnoSyn
3.2 Gram(s)
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 1.5mg
📊 Market median: 500.0mg (143 products)
This product: 1mg
1 Gram(s)
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 1mg
C4 Ultimate Energy & Focus Blend
708 mg

Other Ingredients

Water Natural & Artificial flavors Sucralose Acesulfame Potassium FD&C Yellow #6

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: Consume one bottle (11.66 fl oz) of C4 Ultimate On The Go 20-30 minutes before dominating exercise...and life. Some individuals may experience a harmless tingling sensation, which is attributed to beta alanine.

⚠️ Warnings & Precautions

300mg caffeine

Some individuals may experience a harmless tingling sensation, which is attributed to beta alanine. Warning: This product is only intended to be consumed by healthy adults, 18 years of age or older.

Do not use this product if you are pregnant or nursing. Before using this product consult a licensed, qualified, health care professional, including but not limited to, if: you are taking antidepressants such as a MAOI (Monoamine Oxidase Inhibitor) or SSRI, blood thinners, nonsteroidal anti-inflammatory drugs, pseudoephedrine, or you are taking any other dietary supplement, prescription drug or over-the-counter medication; or if, you suspect you have or have been treated for, diagnosed with or have a family history of, any medical condition, including but not limited to: high or low blood pressure, diabetes, glaucoma, anxiety, cardiovascular, psychiatric or seizure disorders, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, or difficulty urinating due to prostate enlargement. This product contains caffeine and should not be used by individuals wishing to eliminate caffeine from their diet or in combination with caffeine or stimulants from other sources, including but not limited to, coffee, tea, soda, or other dietary supplements and medications.

Discontinue use 2 weeks prior to surgery. Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing.

Keep out of reach of children.

🧪 Formulation Notes

300mg caffeine

This product contains caffeine and should not be used by individuals wishing to eliminate caffeine from their diet or in combination with caffeine or stimulants from other sources, including but not limited to, coffee, tea, soda, or other dietary supplements and medications.

Additional Information

Made in the U.S.A. using U.S. and imported ingredients and components.

For complete patent and trademark information visit cellucor.com/c4ultimate

The most explosive pre-workout

Naturally & artificially flavored 12 pack 12 - 11.66 fl oz bottles (139.9 fl oz) 12 - 345 mL bottles (4.14 L)

Store in a cool dry place. Do not freeze.

105466

Product Details

UPC / SKU 8 42595 10262 8
DSLD Entry Date 2018-01-25
Product Type Other Combinations
Form Liquid
Brand Cellucor
DSLD ID 82832
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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