5-Hour Energy Grape by Living Essentials — Ingredients, Evidence & Safety

Product Label

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Label Data

1.93 fl. Oz. Serving Size

Other Combinations Product Type

67% Evidence Coverage

Supplement Facts — Evidence Check

Niacin

30 mg (150% DV)

✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 30mg UL 35mg

Vitamin B6

40 mg (2000% DV)

📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 40mg UL 100mg

Folic Acid

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

500 mcg (8333% DV)

📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.5mg

Sodium

18 mg (1% DV)

Energy Blend

1870 mg

Other Ingredients

purified Water Natural and Artificial flavors Sucralose Potassium Sorbate Sodium Benzoate EDTA

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years)

Product Information

📋 Directions for Use

RECOMMENDED USE: Take one half (1/2) bottle for moderate energy. Take one whole bottle for maximum energy. Do not exceed two bottles daily, consumed several hours apart. Use or discard any remainder within 72 hours (three days) after opening. Refrigeration not required.

⚠️ Warnings & Precautions

CAUTION: Contains caffeine comparable to a cup of the leading premium coffee. Limit caffeine products to avoid nervousness, sleeplessness, and occasional rapid heartbeat. You may experience a Niacin Flush (hot feeling, skin redness) that lasts a few minutes. This is caused by Niacin (Vitamin B3) increasing blood flow near the skin.

Do not take if you are pregnant or nursing, or under 12 years of age. If you are taking medication and/or have a medical condition, consult your doctor before use.

🧪 Formulation Notes

amino acids

b-vitamins

Phenylketonurics: Contains phenylalanine.

K

Sugar free

zero sugar

Additional Information

4 calories

Hours of energy now - No crash later†

Product Details

DSLD Entry Date 2011-10-26

Product Type Other Combinations

Form Liquid

Brand Living Essentials

DSLD ID 1177

Data Updated 2026-04-11

Research Evidence

241 Research Sources

55 Avg Quality Score

113 Meta Analysis

75 Systematic Review

32 Rct

11 Clinical Trial

3 Other

3 Regulatory Source

1 Cochrane Review

1 Narrative Review

1 Openfda Safety

A Niacin for primary and secondary prevention of cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases

Meta Analysis BMJ (Clinical research ed.) 2013

PubMed DOI

A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients

Meta Analysis BMJ (Clinical research ed.) 2014

PubMed DOI

A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk

Meta Analysis Nature medicine 2024

PubMed DOI

A Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Meta Analysis Nature genetics 2010

PubMed DOI

A Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Meta Analysis Nature genetics 2010

PubMed DOI

A Antidepressants for smoking cessation

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI

A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI Cochrane

B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis

Meta Analysis JAMA network open 2019

PubMed DOI

B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

Meta Analysis JAMA 2016

PubMed DOI

View all evidence for Niacin →