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Mangaplex

product on market Capsule PL Progressive Laboratories Safety: 98/100
98/100

This product looks safe

  • Manganese: 73mg is 6.6× the Tolerable Upper Intake Level (11mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile includes vitamins C, D3, and E, alongside B-vitamins, which are supported by strong evidence for supporting immune function and metabolic health. Research indicates these nutrients play key roles in cellular protection and energy production. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Manganese: 73mg is 6.6× the Tolerable Upper Intake Level (11mg)

Label

Product Label

Label for Mangaplex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
80 mg (133% DV)
50 IU (12.5% DV)
Within RDA (0.1× RDA) 608 studies (A:16, B:251)
10 IU (33% DV)
Within RDA (0.4× RDA) 179 studies (A:3, B:90)
5 mg (333% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
10 mcg (166% DV)
4.2× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
26 mg (2.6% DV)
73 mg (3650% DV)
Exceeds UL by 6.6× (UL: 11 mg) 9 studies — no high-quality reviews
Green Pea Concentrate
200 mg
Horsetail
100 mg
30 mg
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
raw Bovine Liver Concentrate
10 mg
Rose Hips
5 mg

Other Ingredients

Rice Flour Vegetable Lubricant Gelatin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: One capsule daily, or more, as directed by a health care professional.

Warnings & Precautions

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of reach of children.

Contains soy. May contain races of lactose (milk) used in processing.

Formulation Notes

Manganese and Vitamin complex

Contains soy.

Additional Information

Sold only for dispensing by a licensed health care professional.

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Rev. A2014 Reorder No. 426

GMP 3rd party confirmed compliant

PL Since 1972

Metadata

Product Details

UPC / SKU3 51821 00426 6
DSLD Entry Date2017-03-24
Product TypeOther Combinations
FormCapsule
BrandPL Progressive Laboratories
DSLD ID71414
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.