Complete Cardio Heart & Cholesterol Health

product on market Softgel Capsule Irwin Naturals 🟢 Safety: 100/100
Brand: Irwin Naturals
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 71% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Liquid Softgel(s) Serving Size
42 Servings
Other Combinations Product Type
71% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (1000% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
400 mcg (6667% DV)
📊 166.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.4mg
Plant Sterol Esters
650 mg
636 mg
📊 Market median: 750.0mg (447 products) 📚 388 studies (Tier A: 18, B: 204)
This product: 636mg UL 3000mg
200 mg
✅ Within RDA (0.5× RDA of 420 mg)
RDA 420mg This product: 200mg UL 350mg
150 mg
📊 Market median: 333.0mg (166 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 150mg
150 mg
📊 Market median: 250.0mg (182 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 150mg
100 mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 100mg
100 mg
📊 Market median: 99.0mg (52 products) 📚 234 studies (Tier A: 4, B: 113)
RDA 3400mg This product: 100mg
30 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 30mg UL 1200mg
10 mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 10mg
Policosanol
5 mg
BioPerine Complex
6 mg

Other Ingredients

Gelatin purified Water Soy Lecithin Glycerin Beeswax Silicon Dioxide Titanium Dioxide Sodium Copper Chlorophyllin Turmeric

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Full Disclosure Ingredient Panel DIRECTIONS: (Adult) Take two (2) Liquid Soft-Gels twice a day with meals and a full glass of water.

⚠️ Warnings & Precautions

WARNING: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects of other reproductive harm.

Contains: Fish (anchovy, sardine), Soy

Usage Warnings: Do not use if safety seal is broken.

Check with your doctor before using this product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persons under 18. KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

Contains: Fish (anchovy, sardine), Soy

No preservatives added.

CoQ10 ~Phytosterols ~ B-Vitamins

Additional Information

Diet & Exercise Program available online at www.irwinNaturals.com/deplan

May Reduce the Risk of Heart Disease

To join our Wellness Club and receive tips on how to improve your health, please visit us at www.IrwinNaturals.com/wellness1

Many factors influence cardiovascular function and can create considerable challenges to maintaining optimal heart and blood vessel health. This robust formula, in conjunction with a healthy diet and exercise program, can support heart function, help maintain healthy cholesterol levels and protect the body from the oxidative effects of stress and aging.* ~Supports Heart and Vascular Function: Powerful nutrients and botanical ingredients in this formula have been studied for their ability to promote healthy function of the heart muscle and vascular system. ~Protects Against Oxidative Stress: Antioxidants in this formula target free radicals in the vascular system, while B-vitamins support healthy homecystein levels. ~May reduce the Risk of Heart Disease: Consuming 1300 mg of plant sterol esters twice daily, as part of a diet low in saturated fat and cholesterol, can help maintain healthy cholesterol levels and may reduce the risk of heart disease. A daily serving of Complete Cardio Heart & Cholesterol Health supplies 1300 mg of plant sterol esters. This all-in-one, comprehensive product combines key ingredients into one innovative formula to support overall cardiovascular health.

QUESTIONS: Call Consumer Affairs 1-800-297-3273 Weekdays 8:00 AM to 5:00 PM (PST)

We employ compliance testing to ensure purity and potency.

QUALITY TESTED PASS GUARANTEED

{Globe} Global Responsibility - Over the years we have donated to organizations that support the environment and the health of our children.

Store in a cool dry place.

What makes us different: Liquid Soft-Gels- The nutrients in these easy-to-swallow Liquid Soft-Gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft-Gels provide an optimum delivery system.

3042-LAB-06/13 INO36841 V8

Product Details

UPC / SKU 7 10363 56841 2
DSLD Entry Date 2015-04-24
Product Type Other Combinations
Form Softgel Capsule
Brand Irwin Naturals
DSLD ID 44743
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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