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Integra Plus

product on market Capsule US Pharmaceutical Corporation Safety: 93/100
93/100

This product looks safe

  • Ferrous Fumarate: 191.1mg is 4.2× the Tolerable Upper Intake Level (45mg)
  • Polysaccharide Iron Complex: 135.9mg is 3.0× the Tolerable Upper Intake Level (45mg)
  • 91% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines iron sources and B vitamins to support red blood cell production and oxygen transport. Strong clinical evidence supports the use of iron and folic acid for managing anemia, while vitamin C enhances iron absorption. The ingredient profile is supported by moderate to strong research across its primary components.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Ferrous Fumarate: 191.1mg is 4.2× the Tolerable Upper Intake Level (45mg)

Polysaccharide Iron Complex: 135.9mg is 3.0× the Tolerable Upper Intake Level (45mg)

Label

Product Label

Label for Integra Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Multi-Vitamin and Mineral (MVM)
Product Type
91%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

191.1 mg
Exceeds UL by 4.2× (UL: 45 mg) 505 studies (A:17, B:273)
135.9 mg (694% DV)
Exceeds UL by 3.0× (UL: 45 mg) 505 studies (A:17, B:273)
Vitamin C
210 mg (350% DV)
1 mg (250% DV)
2.5× RDA — within safe limits 226 studies (A:10, B:105)
5 mg (333% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (294% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
20 mg (100% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
7 mg (70% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
25 mg (1250% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
10 mcg (166% DV)
4.2× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Hypromellose Silicon Dioxide Magnesium Stearate Titanium Dioxide FDA/E172 Yellow Iron Oxide FD&C Red #40 FD&C Blue #1
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

DOSAGE AND ADMINISTRATION: Adults (persons over 12 years of age), one (1) capsule daily, between meals, or as prescribed by a physician.

Warnings & Precautions

Do not exceed recommended dosage.

CAUTION: Rx only.

WARNING: Accidental overdose of iron-containing products is the leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Do not administer to children under the age of 12.

Additional Information

Store at controlled room temperature 15(0) to 30(0) C (59(0) to 86(0) F). Keep in a cool, dry place.

Capsules are not USP.

US(R)

Also for treatment of condition in which iron deficiency and vitamin C deficiency occur together, along with a deficient intake or increased need for B-Complex vitamins in chronic and acute illness, as well as cases of metabolic stress, and in convalescence.

Rev. 01/2009 LC-10810

Rx Only

Consult package insert for full prescription information.

Metadata

Product Details

UPC / SKU5274771260
DSLD Entry Date2014-10-27
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
DSLD ID37078
Data Updated2026-04-11
Research

Research Evidence

566
Research Sources
56
Avg Quality
240
Meta Analysis
100
Clinical Trial
74
Systematic Review
71
Guideline
58
Rct
11
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
1
Observational
1
Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025 PubMed DOI
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024 PubMed DOI
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.