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Stress B-Complex

product on market Capsule Thorne Safety: 92/100
92/100

This product looks safe

  • Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
  • Folate: 334mg is 334.0× the Tolerable Upper Intake Level (1.0mg)
  • 89% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The B-complex vitamins in this profile support energy metabolism and neurological function, with strong evidence supporting their role in cellular health. These nutrients are essential for converting food into fuel and maintaining cognitive processes. The high safety score indicates a favorable profile for general consumption.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)

Folate: 334mg is 334.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Stress B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Vitamin
Product Type
89%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
28.6 mg (2200% DV)
22.0× RDA — above typical dose 13 studies (A:0, B:1)
80 mg (500% DV)
Exceeds UL by 2.3× (UL: 35 mg) 196 studies (A:5, B:63)
28.4 mg (1671% DV)
21.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
334 mcg DFE (84% DV)
Exceeds UL by 334.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
100 mcg (4167% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
80 mcg (267% DV)
2.7× RDA — within safe limits 27 studies (A:0, B:11)
250 mg (5000% DV)
50.0× RDA — above typical dose 2 studies — no high-quality reviews
14 mg (3% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)

Other Ingredients

Hypromellose Microcrystalline Cellulose Calcium Laurate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 capsule one to three times daily or as recommended by your healthcare practitioner.

Warnings & Precautions

Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Formulation Notes

Foundational Stress

Gluten free

This product uses Gnosis S.p.A.’s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic). Quatrefolic is a registered trademark of Gnosis S.p.A.

Additional Information

Store tightly sealed in a cool, dry place.

Manufactured in the USA Using US & Imported Ingredients NSF Contents Certified

Metadata

Product Details

UPC / SKU6 93749 00296 3
DSLD Entry Date2025-08-22
Product TypeVitamin
FormCapsule
BrandThorne
DSLD ID336307
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.