🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 83% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
83% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (1538% DV)
📊 15.4× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 20mg
20 mg (1176% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
📊 Market median: 5.0mg (298 products) 📚 701 studies (Tier A: 5, B: 123)
This product: 500mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 500mg

Other Ingredients

Capsule Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: Take two capsules once or twice daily or as directed by your physician.

⚠️ Warnings & Precautions

Keep out of reach of children

Do not use if pregnant or nursing.

Stop use if adverse reactions develop.

🧪 Formulation Notes

Full spectrum methylation support

Gluten free Soy free Dairy free Gluten, soy & dairy free

Additional Information

Storage: Keep tightly closed in a dry place at room temperature. (59-86 degrees F or 15-30 degrees C)

Product Details

UPC / SKU 7 28650 05408 1
DSLD Entry Date 2025-09-25
Product Type Other Combinations
Form Capsule
Brand NutraMedix
DSLD ID 334106
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
View all evidence for Riboflavin →

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