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Vitamin B Complex

product on market Capsule Pure Herbs Safety: 87/100
87/100

This product is generally safe

  • Folate: 222mg is 222.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 82% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The B-complex vitamins, including thiamine, riboflavin, and niacin, are supported by strong evidence for their roles in energy metabolism and neurological function. These ingredients facilitate the conversion of nutrients into cellular energy. Research indicates a high safety profile for these essential nutrients when taken within recommended dosages.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 222mg is 222.0× the Tolerable Upper Intake Level (1.0mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Vitamin B Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
100
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

33 mg (2750% DV)
27.5× RDA — above typical dose 76 studies (A:0, B:33)
33 mg (2530% DV)
25.4× RDA — above typical dose 13 studies (A:0, B:1)
33 mg NE (200% DV)
2.4× RDA — within safe limits 196 studies (A:5, B:63)
33 mg (1940% DV)
25.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
222 mcg DFE (50% DV)
Exceeds UL by 222.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
33 mcg (1370% DV)
13.8× RDA — above typical dose 139 studies (A:1, B:44)
100 mcg (330% DV)
3.3× RDA — above typical dose 27 studies (A:0, B:11)
33 mg (660% DV)
6.6× RDA — above typical dose 2 studies — no high-quality reviews
33 mg (6% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
33 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Proprietary Blend
164 mg

Other Ingredients

Gelatin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one capsule daily or as directed by your healthcare practitioner.

Warnings & Precautions

This bottle is sealed for your protection. Do not use if inner seal has been tampered with or damaged.

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Additional Information

NE- Niacin Equivalents, DFE- Dietary Folate Equivalents

Metadata

Product Details

DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormCapsule
BrandPure Herbs
DSLD ID327254
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.