Hepatizol by ProEnzol — Ingredients, Evidence & Safety

🟢 97/100

This product looks safe

Folate: 70mg is 70.0× the Tolerable Upper Intake Level (1.0mg)
64% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 70mg is 70.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Vegan Capsule(s) Serving Size

60 Servings

Other Combinations Product Type

64% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1500 mcg RAE (167% DV)

Thiamine

2.2 mg (183% DV)

✅ 1.8× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 2.2mg

Riboflavin

2 mg (154% DV)

✅ 1.5× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 2mg

Niacin

3.4 mg NE (21% DV)

✅ Within RDA (0.2× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 3.4mg UL 35mg

Pyridoxine

2.2 mg (130% DV)

✅ 1.7× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2.2mg UL 100mg

Folate

70 mcg DFE (18% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 70.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 70mg UL 1.0mg

Vitamin B12

500 mcg (208% DV)

📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.5mg

Pantothenic Acid

3.8 mg (76% DV)

✅ Within RDA (0.8× RDA of 5 mg) 📚 1 studies — no high-quality reviews

RDA 5mg This product: 3.8mg

Zinc

10 mg (91% DV)

✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 10mg UL 40mg

Hepatic Support Blend

970 mg

pHysioProtease

60 mg

Other Ingredients

Plant Fiber Water

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: take two (2) capsules one to two (1-2) times twice daily on an empty stomach, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Caution: if you are pregnant, nursing, have a serious medical condition, or take any medications, consult your healthcare professional before use.

Use only if tamper-evident seal is unbroken.

Keep out of reach of children.

Exclusively for professionals

🧪 Formulation Notes

ProEnzol Heptizol provides a beneficial blend of powerful herbal extracts all-natural B-vitamins and pHysioProtease to help maintain a healthy liver by supporting normal toxin elimination, bile composition, macronutrient metabolism, immune modulation and liver tissue protection.

Assists in maintaining healthy liver structure and function

Contains no: sugar, soy, wheat, yeast, gluten, peanuts, tree nuts, eggs, dairy, animal products, artificial colors, flavors and sweeteners or genetically modified organisms (GMOs).

Additional Information

Store tightly closed in a cool, dry place.

Product Details

UPC / SKU 7 07636 12102 3

DSLD Entry Date 2024-12-21

Product Type Other Combinations

Form Capsule

Brand ProEnzol

DSLD ID 322841

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →