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Migranex +BioPerine

product on market Capsule Approved Science Safety: 97/100
97/100

This product looks safe

  • Magnesium: 360mg is 1.0× the Tolerable Upper Intake Level (350mg)
  • 46% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Butterbur and feverfew are supported by moderate evidence for reducing migraine frequency and severity. Magnesium and B vitamins serve as complementary nutrients often used for neurological support. Overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 360mg is 1.0× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Migranex +BioPerine
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
46%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (30769% DV)
307.7× RDA — above typical dose 13 studies (A:0, B:1)
360 mg (86% DV)
Exceeds UL by 1.0× (UL: 350 mg) 316 studies (A:8, B:159)
10 mg NE (63% DV)
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
Butterbur
150 mg
Market median: 380.0mg (120 products) 8 studies — no high-quality reviews
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)
Market median: 120.0mg (440 products) 191 studies (A:1, B:71)
Wild Yam, Powder
10 mg
10 mg
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
White Willow, Powder
10 mg
BioPerine
10 mg

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two capsules daily, (one in the morning and one in the afternoon), with meals and an 8 oz. glass of water.

Warnings & Precautions

Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement. Keep out of reach children.

Formulation Notes

Manufactured in the USA according to current Good Manufacturing Practice (cGMP) and conforms to the tested ingredients grade, strength and purity of industry Quality Standards.

Vegan friendly

Made with GMO free ingredients

Advanced migraine support Premium grade High potency Safe Fast Natural formula Optimal strength GMP Certified

Contains BioPerine and Feverfew

100% vegan friendly

Additional Information

Store at room temperature.

Vegan friendly Made in USA No animal testing GMP Good Manufacturing Practice Quality Product

Metadata

Product Details

UPC / SKUX001CDLLET
DSLD Entry Date2024-11-22
Product TypeOther Combinations
FormCapsule
BrandApproved Science
DSLD ID319791
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.