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Coenzyme B-Complex

product on market Capsule Woodstock Vitamins Safety: 92/100
92/100

This product looks safe

  • Niacin: 140mg is 4.0× the Tolerable Upper Intake Level (35mg)
  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 90% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The B-complex vitamins, including thiamine, riboflavin, and folate, are supported by strong evidence for their roles in energy metabolism and neurological function. These nutrients are essential for cellular processes and cognitive health. The current formulation maintains a high safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 140mg is 4.0× the Tolerable Upper Intake Level (35mg)

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Coenzyme B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
180
Servings
Vitamin
Product Type
90%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg (1667% DV)
16.7× RDA — above typical dose 76 studies (A:0, B:33)
20 mg (1538% DV)
15.4× RDA — above typical dose 13 studies (A:0, B:1)
140 mg (875% DV)
Exceeds UL by 4.0× (UL: 35 mg) 196 studies (A:5, B:63)
20 mg (1176% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
400 mcg (16667% DV)
166.7× RDA — above typical dose 139 studies (A:1, B:44)
400 mcg (1333% DV)
13.3× RDA — above typical dose 27 studies (A:0, B:11)
150 mg (3000% DV)
30.0× RDA — above typical dose 2 studies — no high-quality reviews
30 mg (5% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
20 mg
16.7× RDA — above typical dose 76 studies (A:0, B:33)

Other Ingredients

Hydroxypropyl Methylcellulose Stearic Acid Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one capsule once or twice daily, or as directed by your healthcare practitioner.

Warnings & Precautions

Consult your healthcare practitioner prior to use.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Storage: Keep closed in a cool, dry place out of reach of children.

Professional use only

Formulation Notes

Coenzyme B-Complex contains the entire spectrum of B vitamins to support adrenal, neurological, and stress-related functions. It features activated forms of vitamins B2, B6, and B12; benfotiamine, a fat soluble, more physiologically active form of thiamin; and folate as Quatrefolic, which is proven to have greater stability, solubility, and bioavailability over calcium salt forms of 5-MTHF.

Does not contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

B complex with benfotiamine and Quatrefolic

Manufactured in a GMP compliant facility.

Vegetarian caps

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

This package is completely recyclable

Metadata

Product Details

UPC / SKU6 69439 84607 0
DSLD Entry Date2024-04-23
Product TypeVitamin
FormCapsule
BrandWoodstock Vitamins
DSLD ID310181
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.