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B-Complex

product on market Capsule Healthy Origins Safety: 94/100
94/100

This product looks safe

  • Vitamin B3: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Vitamin B9: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 83% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This B-complex contains vitamins B1, B2, B3, B5, and B6, which are essential for energy metabolism and neurological function. There is strong research evidence supporting the role of these nutrients in cellular energy production. The formulation maintains a high safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B3: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Vitamin B9: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
83%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (31% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
500 mcg (1666% DV)
16.7× RDA — above typical dose 27 studies (A:0, B:11)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
500 mcg (20833% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
25 mg (5% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
Pantethine
10 mg
4.2× RDA — above typical dose 76 studies (A:0, B:33)
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Hypromellose Water Microcrystalline Cellulose Silicon Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement for adults, take one (1) vegetarian capsule daily, preferably with a meal, or as directed by a health care professional.

Warnings & Precautions

Keep out of reach of children.

Caution: Consult a physician before use if you are pregnant, nursing, taking medication or have a medical condition.

Formulation Notes

Healthy Origins Bioavailable B-Complex contains all eight B vitamins in their active, coenzyme forms for optimal absorption. B vitamins are a group of nutrients that are essential for our overall health and well-being. They provide an extensive range of support for the body, but they are commonly known for their pivotal roles in neurological health, cognitive health, energy production and cellular function.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, peanut or tree nut derived ingredients.

Manufactured in a cGMP facility.

Bioavailable Supports neurological and cognitive health

Non GMO

Suitable for vegans

Additional Information

Store in a cool, dry place.

New look

3rd party tested

DFE = Dietary Folate Equivalent

Metadata

Product Details

UPC / SKU6 03573 24902 1
DSLD Entry Date2024-01-24
Product TypeOther Combinations
FormCapsule
DSLD ID305553
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.