🟢 92/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 50mg is 50.0× the Tolerable Upper Intake Level (1.0mg)
  • 89% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 50mg is 50.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Vegetarian Capsule(s) Serving Size
50 Servings
Other Combinations Product Type
89% Evidence Coverage

Supplement Facts — Evidence Check

12 mg (1000% DV)
📊 10.0× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 12mg
50 NE (332% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
10 mg (769% DV)
📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 10mg
12 mg (706% DV)
📊 9.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 12mg UL 100mg
50 mcg DFE (21% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 50.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 50mg UL 1.0mg
100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
100 mcg (333% DV)
📊 3.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.1mg
20 mg (400% DV)
📊 4.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 20mg
800 mg
📊 Market median: 500.0mg (223 products) 📚 22 studies (Tier A: 0, B: 1)
This product: 800mg

Other Ingredients

Cellulose Calcium Carbonate Silica Leucine

Label Claims — Verification

All Other
All Other (98% of products) Structure/Function (78% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Recommendations Take 2 capsules 1 to 2 times daily, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Keep out of reach of children

Use only if safety seal is intact

Warning If pregnant, consult your physician before taking.

🧪 Formulation Notes

Excludes coatings, binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, sugar. Verified by independent testing

Raw materials and finished products are independently tested by U.S. labs. Learn more at vitalnutrients.net

Additional Information

Store sealed in a cool dry place

Product Details

UPC / SKU 6 93465 50811 4
DSLD Entry Date 2024-12-21
Product Type Other Combinations
Form Capsule
DSLD ID 305168
Data Updated 2026-04-11

Research Evidence

50 Research Sources
47 Avg Quality Score
28 Rct
13 Clinical Trial
5 Guideline
4 Systematic Review
A Using a Novel Consensus-Based Chemoinformatics Approach to Predict ADMET Properties and Druglikeness of Tyrosine Kinase Inhibitors.
Guideline International journal of molecular sciences 2025
B Australia and New Zealand consensus statement on the cardiovascular management of patients with chronic lymphocytic leukaemia treated with Bruton's tyrosine kinase inhibitors.
Guideline Internal medicine journal 2025
B Branched-chain amino acid supplementation for improving growth and development in term and preterm neonates
Systematic Review The Cochrane database of systematic reviews 2020
B [Clinical practice guideline on anaplastic lymphoma kinase-tyrosine kinase inhibitors for non-small cell lung cancer (2025 edition)].
Guideline Zhonghua zhong liu za zhi [Chinese journal of oncology] 2025
B [Chinese expert consensus on epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer (2025 edition)].
Guideline Zhonghua yi xue za zhi 2025
B Consensus Guideline for the Diagnosis and Treatment of Tyrosine Hydroxylase (TH) Deficiency.
Guideline Journal of inherited metabolic disease 2025
B Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating
Rct Cognitive, affective & behavioral neuroscience 2020
B Effect of Amino Acid Supplementation on Iron Regulation after Endurance Exercise
Rct Nutrients 2023
C Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression
Systematic Review Sports medicine - open 2024
C The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review
Systematic Review Plant foods for human nutrition (Dordrecht, Netherlands) 2020
View all evidence for Tyrosine →

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