🟢 98/100

This product looks safe

  • Folate: 515mg is 515.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 515mg is 515.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
64% Evidence Coverage

Supplement Facts — Evidence Check

2.6 mg (217% DV)
✅ 2.2× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 2.6mg
3 mg (231% DV)
✅ 2.3× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 3mg
25 mg (156% DV)
✅ 1.8× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 25mg UL 35mg
11 mg (647% DV)
📊 8.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 11mg UL 100mg
515 mcg DFE (129% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 515.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 515mg UL 1.0mg
300 mcg (12500% DV)
📊 125.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.3mg
150 mcg (500% DV)
📊 5.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.15mg
12.5 mg (250% DV)
✅ 2.5× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 12.5mg
Calcium
150 mg (12% DV)
7.5 mg (68% DV)
✅ Within RDA (0.7× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 7.5mg UL 40mg
Beta-Sitosterol
250 mg
Artichoke Leaf Extract
250 mg
📊 Market median: 333.0mg (166 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 75mg
Policosanol
10 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Hypromellose Polyethylene Glycol Hydroxypropyl Cellulose Silica Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

🧪 Formulation Notes

Cardiovascular maintenance

Homocysteine Support Formula

Product Details

DSLD Entry Date 2023-11-22
Product Type Other Combinations
Form Tablet or Pill
Brand Heart Health
Bundle Heart Health System
DSLD ID 298840
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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