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Hot & Skinny

product on market Capsule Angry Supplements Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The profile contains B-complex vitamins and Vitamin E, which support cellular energy metabolism and antioxidant functions. Research provides strong evidence for the role of these nutrients in maintaining general metabolic health. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Hot & Skinny
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

13.4 mg (89% DV)
Within RDA (0.9× RDA) 179 studies (A:3, B:90)
2 mg (167% DV)
1.7× RDA — within safe limits 76 studies (A:0, B:33)
5 mg (385% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
20 mg (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
3 mg (176% DV)
2.3× RDA — within safe limits 114 studies (A:3, B:35)
100 mcg (4167% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
10 mg (200% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews
24 mcg (69% DV)
Within RDA (0.7× RDA) 199 studies (A:1, B:55)
Market median: 600.0mg (321 products) 5 studies — no high-quality reviews
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 495.0mg (70 products)
Yerba Mate
50 mg
Cayenne Pepper
50 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews

Other Ingredients

Gelatin Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Adults take two (2) capsules once daily, preferably with a well-balanced meal and water or as directed by a healthcare professional.

Warnings & Precautions

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Formulation Notes

Zero artificial chemicals or preservatives

Body balancing Thermogenic aid

Additional Information

Store in a cool, dry place.

GMP Good Manufacturing Practice Made in the USA With Globally Sourced Ingredients

Metadata

Product Details

UPC / SKU7 00465 36073 1
DSLD Entry Date2023-07-18
Product TypeOther Combinations
FormCapsule
DSLD ID294598
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
View all evidence for Vitamin E →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.