Pure Defense Mushroom-8 Immune Support

product on market Softgel Capsule Irwin Naturals 🟢 Safety: 100/100
Brand: Irwin Naturals
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 32% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

3 Liquid Softgel(s) Serving Size
20 Servings
Botanical with Nutrients Product Type
32% Evidence Coverage

Supplement Facts — Evidence Check

Calories
30 Calorie(s)
Total Fat
2 Gram(s) (3% DV)
Total Carbohydrates
2 Gram(s) (1% DV)
Protein
1 Gram(s)
Vitamin C
200 mg (222% DV)
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
55 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.055mg UL 0.4mg
Extra Virgin Olive Oil
1050 mg
1050 mg
📊 Market median: 1000.0mg (212 products) 📚 12 studies (Tier A: 0, B: 3)
This product: 1050mg
200 mg
📊 Market median: 470.0mg (230 products) 📚 9 studies (Tier A: 3, B: 3)
This product: 200mg
200 mg
📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)
This product: 200mg
200 mg
📊 Market median: 175.0mg (497 products) 📚 11 studies (Tier A: 0, B: 1)
This product: 200mg
100 mg
📊 Market median: 420.0mg (127 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 100mg
100 mg
📊 Market median: 340.0mg (243 products) 📚 3 studies — no high-quality reviews
This product: 100mg
organic Turkey Tail Mushroom powder
100 mg
Organic Agaricus Mushroom powder
50 mg
organic Chaga Mushroom powder
50 mg
organic Cordyceps Mushroom powder
50 mg
organic Lion's Mane Mushroom powder
50 mg
organic Maitake Mushroom powder
50 mg
organic Shiitake Mushroom powder
50 mg
BioPerine Complex
6 mg

Other Ingredients

Gelatin Water, Purified Glycerin Beeswax Soy Lecithin St. John's Bread Maltodextrin Titanium Dioxide Silicon Dioxide

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Organic

Product Information

📋 Directions for Use

This product can be used daily or on an as-needed basis to support your immune system.

Directions: (Adult) for general immune support, take three (3) liquid soft-gels daily with a meal and a full glass of (8oz) of water.

⚠️ Warnings & Precautions

Usage warnings: do not use if safety seal is broken.

Check with your doctor before using this product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persons under 18. Keep out of reach of children.

Contains: soy

🧪 Formulation Notes

This dynamic formula features some of nature's most prized immune-supporting ingredients that have been carefully sourced for maximized purity and potency. We've combined eight powerful mushroom varieties with traditional herbs and nutrients to deliver unparalleled immune-support designed for daily use. 8-mushroom blend Our organic mushrooms are grown in the USA by expert scientists in the field of mycology. Featured in this dynamic formula are eight carefully selected mushroom varieties including reishi, maitake, shitake, Turkey tail, lions mane, chaga, Cordyceps, and agaricus blazei. Traditional herbs & immune supportive nutrients Our 8-mushroom blend is combined with targeted immune-supportive nutrients including vitamin C & zinc, as well as an impressive cohort of traditional immune-boosting herbs from around the world including echinacea, and black elderberry from western herbal traditions, along with licorice, and astragulus from eastern herbal traditions.

What makes us different: Liquid soft-gels - The nutrients in these easy-to-swallow liquid soft gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced liquid soft-gels provide an optimum delivery system.

PASS Quality tested guaranteed Quality assurance - Irwin natural’s is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency.

Patented BioPerine - Our special BioPerine Complex enhances the bioavailability, absorption and potency of many nutrients.

Plus black elderberry

A powerful combination of vitamin C, zinc, echinacea, 8 mushrooms and more

This product contains 9% organic ingredients.

No preservatives added.

Additional Information

Finally, everything you are looking for in a single bottle.

Global responsibility - over the years we have donated to organizations that support the environment and the health of our children.

Store in a cool, dry place.

Questions: Contact Consumer Affairs 1-800-297-3273 Weekdays 8:00 am to 5:00 pm (PST) Questions@irwinnaturals.com 100+ Highly specialized products: www.irwinnaturals.com

Full disclosure ingredient panel

Product Details

UPC / SKU 7 10363 59715 3
DSLD Entry Date 2023-05-24
Product Type Botanical with Nutrients
Form Softgel Capsule
Brand Irwin Naturals
DSLD ID 292087
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI Cochrane
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
PubMed DOI
View all evidence for Vitamin C →

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