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2-in-1 Kidney & Liver Super Cleanse

product on market Softgel Capsule Irwin Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The listed top ingredients consist of basic macronutrients, which provide general energy and structural support rather than targeted therapeutic effects. There is strong evidence for the roles of proteins and carbohydrates in basic human physiology. However, these components do not provide specific evidence for kidney or liver detoxification.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 2-in-1 Kidney & Liver Super Cleanse
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Liquid Softgel(s)
Serving Size
20
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
30 Calorie(s)
Total Fat
2 Gram(s) (2% DV)
Cholesterol
15 mg (4% DV)
Total Carbohydrates
3 Gram(s) (1% DV)
Protein
1 Gram(s)
Vitamin C
50 mg (56% DV)
4 mcg (20% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
15 mg (882% DV)
11.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
12.5 mg (3% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
7.5 mg (68% DV)
Within RDA (0.7× RDA) 263 studies (A:6, B:134)
50 mcg (91% DV)
Within RDA (0.9× RDA) 173 studies (A:0, B:67)
Potassium
25 mg (1% DV)
1600 mg
Market median: 750.0mg (447 products) 393 studies (A:18, B:204)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Pacran SP Cranberry (Vaccinium macrocarpon) powder
250 mg
Artichoke leaf extract
187.5 mg
Stinging Nettle leaf extract
150 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Corn Silk extract
100 mg
Market median: 175.0mg (497 products) 11 studies (A:0, B:1)
Market median: 300.0mg (159 products)
Uva Ursi leaf extract
50 mg
N-Acetyl-Cysteine
45 mg
Market median: 340.0mg (243 products) 3 studies — no high-quality reviews
BioPerine Complex
3 mg

Other Ingredients

Gelatin Water, Purified Glycerin Beeswax Mannitol Soy Lecithin Annatto Dextrin Turmeric Silicon Dioxide Titanium Dioxide Sodium Copper Chlorophyllin Maltodextrin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: (Adults) Take three (3) liquid soft-gels twice daily with a meal and a full glass (8oz) of water. This product is intended for short term use only. Limit use to 10 consecutive days. Optimal hydration should be maintained throughout duration of use.

Warnings & Precautions

This product is not intended for ongoing daily use.

Usage Warnings: Do not use if safety seal is broken.

Check with your doctor before using this product if you are using medication, including heart medications, or have any medical conditions, including a history of kidney stones. Do not use if you have a bile duct obstruction. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persons under 18. Keep out of reach of children.

Contains: Fish (anchovy, sardine), soy

Formulation Notes

2-in-1 Kidney & Liver Super Cleanse is a high-powered whole-body cleansing formula for the health conscious individual who is seeking robust 10-day detoxification support. This dynamic formula utilizes some of Nature's most prized liver and kidney supportive botanicals to encourage detoxification, and the removal of impurities by the kidneys and liver.

Kidney Support Stinging nettle, dandelion leaf and corn silk extracts are valuable botanicals used in traditional formulas that support the cleansing function of the kidneys. PACran is a powerful cranberry extract that has been clinically shown to support the health of the urinary tract while also helping to reduce urinary tract discomfort. Fish oil, zinc, magnesium and potassium helps to support the kidneys as they take on a heavy work load. Liver Support Our milk thistle delivers over 240 mg of silymarin per day for optimal liver support. Artichoke, barberry and reishi mushroom has a long history of traditional use in liver formulas. When combined with n-acetyl-cysteine (NAC) these nutrients give unparalleled support to the liver as it works to process accumulated toxins and impurities.

Use periodically for intense support to the body's detoxification pathways.

What makes us different: Liquid soft-gels - the nutrients in these easy-to-swallow liquid soft-gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced liquid soft-gels provide an optimum delivery system.

Quality assurance- Irwin Naturals is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency.

Patented BioPerine- Our special BioPerine Complex enhances the bioavailability absorption and potency of may nutrients.

Perfectly balanced cleansed and detox with powerful milk thistle and PACran. Plus dandelion & reishi mushroom

No preservatives added.

10-Day Super Cleanse

Additional Information

Store in a cool, dry place.

Questions: Contact consumer affairs 1-800-297-3273 - Weekdays 8:00 AM to 5:00 PM (PST) Questions@IrwinNaturals.com 100+ Highly specialized products: www.IrwinNaturals.com Full disclosure ingredient panel

Quality tested guaranteed Pass

Metadata

Product Details

UPC / SKU7 10363 59457 2
DSLD Entry Date2023-07-18
Product TypeOther Combinations
FormSoftgel Capsule
DSLD ID292059
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.