🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

3 Liquid Softgel(s) Serving Size
20 Servings
Other Combinations Product Type
38% Evidence Coverage

Supplement Facts — Evidence Check

Calories
30 Calorie(s)
Total Fat
2 Gram(s) (2% DV)
Cholesterol
15 mg (4% DV)
Total Carbohydrates
3 Gram(s) (1% DV)
Protein
1 Gram(s)
Vitamin C
50 mg (56% DV)
4 mcg (20% DV)
✅ Within RDA (0.3× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.004mg UL 0.1mg
15 mg (882% DV)
📊 11.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 15mg UL 100mg
250 mcg (10417% DV)
📊 104.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.25mg
12.5 mg (3% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 12.5mg
7.5 mg (68% DV)
✅ Within RDA (0.7× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 7.5mg UL 40mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
Potassium
25 mg (1% DV)
1600 mg
📊 Market median: 750.0mg (447 products) 📚 388 studies (Tier A: 18, B: 204)
This product: 1600mg UL 3000mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 270mg
Pacran SP Cranberry (Vaccinium macrocarpon) powder
250 mg
Artichoke leaf extract
187.5 mg
Stinging Nettle leaf extract
150 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 100mg
Corn Silk extract
100 mg
📊 Market median: 175.0mg (497 products) 📚 11 studies (Tier A: 0, B: 1)
This product: 65mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 50mg
Uva Ursi leaf extract
50 mg
N-Acetyl-Cysteine
45 mg
📊 Market median: 340.0mg (243 products) 📚 3 studies — no high-quality reviews
This product: 15mg
BioPerine Complex
3 mg

Other Ingredients

Gelatin Water, Purified Glycerin Beeswax Mannitol Soy Lecithin Annatto Dextrin Turmeric Silicon Dioxide Titanium Dioxide Sodium Copper Chlorophyllin Maltodextrin

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: (Adults) Take three (3) liquid soft-gels twice daily with a meal and a full glass (8oz) of water. This product is intended for short term use only. Limit use to 10 consecutive days. Optimal hydration should be maintained throughout duration of use.

⚠️ Warnings & Precautions

This product is not intended for ongoing daily use.

Usage Warnings: Do not use if safety seal is broken.

Check with your doctor before using this product if you are using medication, including heart medications, or have any medical conditions, including a history of kidney stones. Do not use if you have a bile duct obstruction. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persons under 18. Keep out of reach of children.

Contains: Fish (anchovy, sardine), soy

🧪 Formulation Notes

2-in-1 Kidney & Liver Super Cleanse is a high-powered whole-body cleansing formula for the health conscious individual who is seeking robust 10-day detoxification support. This dynamic formula utilizes some of Nature's most prized liver and kidney supportive botanicals to encourage detoxification, and the removal of impurities by the kidneys and liver.

Kidney Support Stinging nettle, dandelion leaf and corn silk extracts are valuable botanicals used in traditional formulas that support the cleansing function of the kidneys. PACran is a powerful cranberry extract that has been clinically shown to support the health of the urinary tract while also helping to reduce urinary tract discomfort. Fish oil, zinc, magnesium and potassium helps to support the kidneys as they take on a heavy work load. Liver Support Our milk thistle delivers over 240 mg of silymarin per day for optimal liver support. Artichoke, barberry and reishi mushroom has a long history of traditional use in liver formulas. When combined with n-acetyl-cysteine (NAC) these nutrients give unparalleled support to the liver as it works to process accumulated toxins and impurities.

Use periodically for intense support to the body's detoxification pathways.

What makes us different: Liquid soft-gels - the nutrients in these easy-to-swallow liquid soft-gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced liquid soft-gels provide an optimum delivery system.

Quality assurance- Irwin Naturals is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency.

Patented BioPerine- Our special BioPerine Complex enhances the bioavailability absorption and potency of may nutrients.

Perfectly balanced cleansed and detox with powerful milk thistle and PACran. Plus dandelion & reishi mushroom

No preservatives added.

10-Day Super Cleanse

Additional Information

Store in a cool, dry place.

Questions: Contact consumer affairs 1-800-297-3273 - Weekdays 8:00 AM to 5:00 PM (PST) Questions@IrwinNaturals.com 100+ Highly specialized products: www.IrwinNaturals.com Full disclosure ingredient panel

Quality tested guaranteed Pass

Product Details

UPC / SKU 7 10363 59457 2
DSLD Entry Date 2023-07-18
Product Type Other Combinations
Form Softgel Capsule
DSLD ID 292059
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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