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B-Complex #6

product on market Capsule Thorne Safety: 92/100
92/100

This product looks safe

  • Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
  • Folate: 334mg is 334.0× the Tolerable Upper Intake Level (1.0mg)
  • 89% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This blend of B vitamins, including thiamine, riboflavin, and folate, supports cellular energy metabolism and neurological function. There is strong evidence for the role of these nutrients in maintaining metabolic health. The profile maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)

Folate: 334mg is 334.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-Complex #6
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Vitamin
Product Type
89%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

40 mg (3333% DV)
33.3× RDA — above typical dose 76 studies (A:0, B:33)
30 mg (2308% DV)
23.1× RDA — above typical dose 13 studies (A:0, B:1)
80 mg (500% DV)
Exceeds UL by 2.3× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5882% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
334 mcg DFE (84% DV)
Exceeds UL by 334.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
100 mcg (4167% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
80 mcg (267% DV)
2.7× RDA — within safe limits 27 studies (A:0, B:11)
45 mg (900% DV)
9.0× RDA — above typical dose 2 studies — no high-quality reviews
14 mg (3% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)

Other Ingredients

Hypromellose capsule Cellulose Calcium Laurate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 capsule daily or as recommended by your health-care practitioner.

Warnings & Precautions

Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Formulation Notes

Foundational

Women's health

Gluten free

Manufactured in the USA using US & imported ingredients

This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic).

Additional Information

Store tightly sealed in a cool, dry place.

NSF Certified for Sport

Metadata

Product Details

UPC / SKU6 93749 10603 6
DSLD Entry Date2023-06-22
Product TypeVitamin
FormCapsule
BrandThorne
DSLD ID291770
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.