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All Day Immune Support Ester-C Effervescent 1000 mg + Electrolytes Natural Orange Flavor

product on market Powder Puritan's Pride Safety: 88/100
88/100

This product is generally safe

  • Folate: 20mg is 20.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 55% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula provides Vitamin C and B vitamins, which have strong evidence for supporting immune function and energy metabolism. The inclusion of thiamine and riboflavin supports cellular processes, though the overall evidence coverage for this specific blend is limited. The product maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 20mg is 20.0× the Tolerable Upper Intake Level (1.0mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for All Day Immune Support Ester-C Effervescent 1000 mg + Electrolytes Natural Orange Flavor
Open Full PDF View on NIH DSLD →
Details

Label Data

10 Gram(s)
Serving Size
21
Servings
Other Combinations
Product Type
55%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
25 Calorie(s)
Total Carbohydrates
6 Gram(s) (2% DV)
Vitamin C
1026 mg (1140% DV)
0.38 mg (32% DV)
Within RDA (0.3× RDA) 76 studies (A:0, B:33)
0.43 mg (33% DV)
Within RDA (0.3× RDA) 13 studies (A:0, B:1)
5 mg (31% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
20 mcg DFE (5% DV)
Exceeds UL by 20.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
25 mcg (1042% DV)
10.4× RDA — above typical dose 139 studies (A:1, B:44)
2.5 mg (50% DV)
Within RDA (0.5× RDA) 2 studies — no high-quality reviews
Calcium
150 mg (12% DV)
150 mg (12% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:3)
60 mg (14% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
2 mg (18% DV)
Within RDA (0.2× RDA) 263 studies (A:6, B:134)
0.5 mg (22% DV)
Within RDA (0.2× RDA) 9 studies — no high-quality reviews
5 mcg (14% DV)
Within RDA (0.1× RDA) 199 studies (A:1, B:55)
90 mg (4% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Sodium
100 mg (4% DV)
Potassium
280 mg (6% DV)
Proprietary Wellness Blend
58 mg

Other Ingredients

Fructose Maltodextrin Malic Acid Citric Acid Beta-Carotene natural Orange flavor Silica Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, pour packet into 4-6 fl. oz. of water one daily. Stir or shake. Take Once Daily

Just take one packet daily with 4-6 fl. oz. of water and you are good to go!

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if packet is torn or open.

Formulation Notes

Clinically studied to last longer than regular vitamin C

B Vitamins to support Energy 24 Hour Immune Support

No Artificial Flavor, No Artificial Sweetener, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish.

Ester-C has been clinically studied to stay in the white blood cells for up to 24 hours, which is longer than regular vitamin C. White blood cells are an important component of the immune system.

100% vegetarian

Non-GMO No artificial sweeteners

Ester-C Effervescent Packets offer 24-hour immune support in a delicious, natural orange flavored formula.

Our superior Ester-C The better vitamin C is clinically studied to last longer than regular vitamin C.

Along with essential vitamins, such as B-6 and B-12 to support energy metabolism and vital electrolytes to aid in metabolic hydration. Ester-C the better vitamin C, has your immune support covered.

Additional Information

Store at room temperature.

QA Quality Assured Made in the USA with select ingredients from around the world

TO REORDER ITEM # 26048 www.puritan.com 1-800-645-1030

21 - 10 g (0.35 oz.) Packets

Percent change (%) of vitamin C in white blood cells over 24 hours 50% 40% 30% 20% 10% 0 Ester-C Regular Vitamin C 2 hr 4 hr 8 hr 24 hr

Metadata

Product Details

DSLD Entry Date2023-06-22
Product TypeOther Combinations
FormPowder
DSLD ID286439
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.