🟢 97/100

This product looks safe

  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • 82% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

3 Capsule(s) Serving Size
30 Servings
Botanical with Nutrients Product Type
82% Evidence Coverage

Supplement Facts — Evidence Check

500 mcg (41667% DV)
✅ Within RDA (0.4× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 0.5mg
3.42 mg (263% DV)
✅ 2.6× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 3.42mg
20 mg NE (125% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
10 mg (588% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
666 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 666.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 666mg UL 1.0mg
600 mcg (25000% DV)
📊 250.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.6mg
40 mg (800% DV)
📊 8.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 40mg
100 mg (24% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
Passion Flower extract
200 mg
100 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 100mg
📊 Market median: 300.0mg (122 products) 📚 22 studies (Tier A: 0, B: 7)
This product: 30mg

Other Ingredients

Hydroxypropyl Methylcellulose Dicalcium Phosphate Maltodextrin Magnesium Stearate Silica Dextrin

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

It can be used regularly, or as needed. For optimal results, make this unique supplement part of your daily routine.

Directions: Adults, take 3 capsules daily, as a dietary supplement or as directed by your doctor.

⚠️ Warnings & Precautions

Do not use if clear safety seal around bottle neck is broken or missing.

Warning: Not for use by pregnant or lactating women. Consult a doctor before use if you are taking medications, have a medical condition or have difficulty swallowing.

Use only as directed.

Keep out of the reach of children.

🧪 Formulation Notes

Roex Calming Balance provides a safe, yet powerful non-addictive tool for reducing stress and enhancing relaxation. This unique nutrient and herbal blend can put you back in control, providing the tools you need to stay calm during periods of anxiety and stress.

Relaxation for stress For healthy relaxation Stress reduction Healthy nervous system function

Additional Information

Store at room temperature, in a dry place.

Product Details

UPC / SKU 6 45245 99090 9
DSLD Entry Date 2023-01-23
Product Type Botanical with Nutrients
Form Capsule
Brand Roex
DSLD ID 279325
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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