MSM Glucosamine Joint Complex by Higher Nature — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
46% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size

90 Servings

Other Combinations Product Type

46% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C

30 mg (38% DV)

Zinc

5 mg (50% DV)

✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 5mg UL 40mg

Copper

250 mcg (25% DV)

✅ Within RDA (0.3× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.25mg UL 10mg

Boron

250 mcg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 0.25mg UL 20mg

Methyl Sulphonyl Methane

450 mg

Glucosamine

150 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 150mg

Ginger rhizome extract

25 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 25mg

Nettle leaf extract

18.75 mg

Celery seed extract

7.5 mg

📊 Market median: 630.0mg (46 products)

Median 630.0mg This product: 7.5mg

Panax ginseng extract

1.5 mg

📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)

This product: 1.5mg

Kelp

5 mg

Other Ingredients

Methyl Sulphonyl Methane Microcrystalline Cellulose Lithothamnion calcarea Glucosamine HCl Ascorbic Acid Magnesium Stearate Ginger rhizome extract Nettle Leaf Extract Zinc Citrate Silicon Dioxide Coating Celery seed extract Kelp Sodium Borate Panax ginseng Extract Copper Citrate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: Take 1-4 tablets a day with meals building gradually. Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

⚠️ Warnings & Precautions

May contain naturally occurring fish and crustacea. Allergy advice: see ingredients in bold.

Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Warning: Do not take if pregnant, breastfeeding or taking blood thinning medication. If you are taking any other medication or have a medical condition, please consult your healthcare professional before using this product.

Storage: Store in a cool, dry place out of reach of children.

🧪 Formulation Notes

May contain naturally occurring fish and crustacea.

No artificial colours, flavours or preservatives. No yeast, added sugar or salt.

Body health Advanced formula Optimal benefit

With vitamin C, copper & zinc 11 active nutrients

Vegetarian and vegan

With 11 active nutrients including 5 plant extracts Contains the superior form of glucosamine With zinc to support bones Vitamin C supports normal collagen formation for normal bones and joints Copper supports normal connective tissue

Additional Information

NRV = Nutrient Reference Value

This product has not been tested on animals.

Storage: Store in a cool, dry place out of reach of children.

Product Details

UPC / SKU 5 031013 101007

DSLD Entry Date 2023-03-22

Product Type Other Combinations

Form Tablet or Pill

Brand Higher Nature

DSLD ID 275909

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →