High Potency Vitamin B Complex

product on market Capsule Lake Avenue Nutrition 🟢 Safety: 92/100
Brand: Lake Avenue Nutrition
🟢 92/100

This product looks safe

  • Niacin: 140mg is 4.0× the Tolerable Upper Intake Level (35mg)
  • Folate: 670mg is 670.0× the Tolerable Upper Intake Level (1.0mg)
  • 90% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 140mg is 4.0× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 670mg is 670.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size
90 Servings
Other Combinations Product Type
90% Evidence Coverage

Supplement Facts — Evidence Check

110 mg (9167% DV)
📊 91.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 110mg
10 mg (769% DV)
📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 10mg
140 mg (875% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 4.0× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 140mg UL 35mg
10 mg (588% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
670 mcg DFE (168% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 670.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 670mg UL 1.0mg
400 mcg (16667% DV)
📊 166.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.4mg
500 mcg (1667% DV)
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg
110 mg (2200% DV)
📊 22.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 110mg
28 mg (5% DV)
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 28mg UL 3500mg
100 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 100mg

Other Ingredients

Modified Cellulose Dicalcium Phosphate Ascorbyl Palmitate Microcrystalline Cellulose Silicon Dioxide

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: Take 1 capsule daily with or without food, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Warnings: Keep out of reach of children.

As with all dietary supplements, it is recommended to consult with a healthcare professional before adding something new to your health and wellness regimen. Sealed for your protection. Do not use if seal is missing or broken.

Not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

🧪 Formulation Notes

Formulated without: GMOs, gluten or soy.

Formulated with Quatrefolic 5-MTHF (5-Methyltetrahydrofolic acid).

Supports energy production & healthy nervous system

Not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 8 98220 02090 4
DSLD Entry Date 2022-08-23
Product Type Other Combinations
Form Capsule
Brand Lake Avenue Nutrition
DSLD ID 274404
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
PubMed Cochrane
View all evidence for Thiamine →

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