🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 46% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
45 Servings
Botanical with Nutrients Product Type
46% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
125 mg (207% DV)
5 mg (33% DV)
✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 5mg UL 40mg
📊 Market median: 250.0mg (50 products)
Median 250.0mg This product: 250mg
100 mg
📊 Market median: 470.0mg (230 products) 📚 9 studies (Tier A: 3, B: 3)
This product: 100mg
📊 Market median: 340.0mg (243 products) 📚 3 studies — no high-quality reviews
This product: 100mg
📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)
This product: 50mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 50mg
Maitake Mushroom Extract
50 mg
50 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 50mg
Shiitake Extract
50 mg
Yarrow extract
50 mg

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Stearic Acid Dextrose Silicon Dioxide Magnesium Stearate Food Glaze Coating

Label Claims — Verification

Nutrient
All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: At first signs of imbalance or depressed resistance, take one tablet daily with or without meals for two weeks.

⚠️ Warnings & Precautions

Not recommended for children under 12 years of age.

Warning: Keep out of reach of children.

Do not exceed suggested use or use during pregnancy without consulting a licensed healthcare professional.

🧪 Formulation Notes

NutriBiotic DefensePlus tablets are a unique formulation combining grapefruit seed extract, vitamin C, echinacea extract, astragalus root, ginger root extract, Oregon grape root, yarrow extract, zinc, and the mushroom extracts of reishi, maitake, and shiitake and are used by healthcare professionals worldwide.

Each tablet has the same mg of grapefruit extract as 25 drops of NutriBiotic GSE Liquid Concentrate.

Maximum Strength

250 mg grapefruit seed extract with echinacea, astragalus, vitamin C, mushroom extracts, Oregon grape root & ginger root

Made without soy, milk, egg, yeast, wheat, sweeteners, preservatives, and GMOs. Gluten free

Additional Information

Please recycle

Not tested on animals

Nitro Pak Naturally fresh Bacteria free environment

Product Details

UPC / SKU 7 28177 01014 0
DSLD Entry Date 2023-01-23
Product Type Botanical with Nutrients
Form Tablet or Pill
Brand NutriBiotic
DSLD ID 273483
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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