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B5 SAP

product on market Capsule NFH Safety: 88/100
88/100

This product is generally safe

  • Niacin: 160mg is 4.6× the Tolerable Upper Intake Level (35mg)
  • Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • L-5-Methylfolate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • 90% of ingredients have research evidence
F Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains a blend of B vitamins that support cellular energy metabolism and neurological function. While research for these individual nutrients is strong, the overall evidence coverage for this specific formulation is limited. The ingredients are generally recognized as safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 160mg is 4.6× the Tolerable Upper Intake Level (35mg)

Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

L-5-Methylfolate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B5 SAP
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Vitamin
Product Type
90%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (8333% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
57.2 mg (4400% DV)
44.0× RDA — above typical dose 13 studies (A:0, B:1)
160 mg NE (1000% DV)
Exceeds UL by 4.6× (UL: 35 mg) 196 studies (A:5, B:63)
56.8 mg (3341% DV)
43.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
340 mcg DFE (85% DV)
Exceeds UL by 340.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
340 mcg DFE (85% DV)
Exceeds UL by 340.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
200 mcg (8333% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
160 mcg (533% DV)
5.3× RDA — above typical dose 27 studies (A:0, B:11)
500 mcg (10000% DV)
Within RDA (0.1× RDA) 2 studies — no high-quality reviews
80 mg (15% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)

Other Ingredients

Vegetable Magnesium Stearate Silicon Dioxide Microcrystalline Cellulose Vegetable Hypromellose Water, Purified
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use: Adults: Take 2 capsules daily with a meal or as directed by your healthcare practitioner. If you are taking other medications, take this product a few hours before or after them.

Do not remove silica pack. Ensure lid is closed properly after each use.

Warnings & Precautions

Do not use if seal is broken.

Keep out of reach of children.

This product is very sensitive to heat and humidity.

Formulation Notes

B5 SAP helps the body to metabolize carbohydrates, fats, and proteins. B5 SAP promotes tissue and red blood cell formation. B5 sap supports normal growth and development.

All ingredients listed for this product lot number have been tested by a third-party laboratory for identity, potency, and purity.

Contains no: Gluten, soy, wheat, corn, eggs, dairy, yeast, citrus, preservatives, artificial flavor or sugar.

This product is non-GMO and vegan friendly.

This product is non-GMO and vegan friendly.

Color, size and smell may vary from one lot to another.

Pantothenic acid

Additional Information

Store in a cool and dry place.

NPN 80061791

Metadata

Product Details

UPC / SKU8 56711 01111 4
DSLD Entry Date2023-01-23
Product TypeVitamin
FormCapsule
BrandNFH
DSLD ID273343
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.