B6 SAP

product on market Capsule NFH 🟢 Safety: 94/100
Brand: NFH
🟢 94/100

This product looks safe

  • Vitamin B3: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
  • L-Methylfolate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 92% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin B3: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
⚠️ L-Methylfolate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
92% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
15 mg (1154% DV)
📊 11.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 15mg
5 mg (650% DV)
📊 3.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 5mg
80 mg (500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 80mg UL 35mg
80 mg (4706% DV)
📊 61.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 80mg UL 100mg
20 mg (1176% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
200 mcg (8333% DV)
📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.2mg
80 mcg (267% DV)
✅ 2.7× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.08mg
50 mg (1000% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
40 mg (7% DV)
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 40mg UL 3500mg
60 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 60mg

Other Ingredients

Vegetable Magnesium Stearate Silicon Dioxide Microcrystalline Cellulose Vegetable Hypromellose Water, Purified

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions for use: Adults: Take 1 capsule daily with a glass of water or juice or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Do not use if seal is broken.

Keep out of reach of children.

🧪 Formulation Notes

B6 SAP helps replenish depleted vitamin B6 stores and supports cardiovascular health, homocysteine metabolism, hemoglobin formation, neurotransmitter synthesis, and antioxidant status.

B6 SAP contains the activated enzyme form pyridoxal-5'-phosphate, in a blend of B vitamins, choline and biotin to support optimal B6 metabolism.

All ingredients listed for this product lot number have been tested by a third-party laboratory for identity, potency, and purity.

Contains no: Gluten, soy, wheat, corn, eggs, dairy, yeast, citrus, preservatives, artificial flavor or color, starch, or sugar.

This product is non-GMO and vegan friendly.

This product is non-GMO and vegan friendly.

Color, size and smell may vary from one lot to another.

Vitamin B6

Made in Canada

Additional Information

This product is very sensitive to heat and humidity Store in a cool and dry place. Do not remove silica pack. Ensure lid is closed properly after each use.

NPN 80045616

Product Details

UPC / SKU 8 56711 00132 0
DSLD Entry Date 2022-09-22
Product Type Other Combinations
Form Capsule
Brand NFH
DSLD ID 272998
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
PubMed Cochrane
View all evidence for Thiamine →

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