Home/ Supplements/ Thiamine/ B6 SAP

B6 SAP

product on market Capsule NFH Safety: 94/100
94/100

This product looks safe

  • Vitamin B3: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
  • L-Methylfolate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 92% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains a complex of B vitamins, including thiamine, riboflavin, niacin, and B6, which are essential for energy metabolism and neurological function. There is strong research evidence supporting the role of these vitamins in cellular health. The product maintains a high safety score, indicating a low risk profile for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B3: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)

L-Methylfolate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B6 SAP
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
92%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
15 mg (1154% DV)
11.5× RDA — above typical dose 13 studies (A:0, B:1)
5 mg (650% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
80 mg (500% DV)
Exceeds UL by 2.3× (UL: 35 mg) 196 studies (A:5, B:63)
80 mg (4706% DV)
61.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
20 mg (1176% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
200 mcg (8333% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
80 mcg (267% DV)
2.7× RDA — within safe limits 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
40 mg (7% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
60 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Vegetable Magnesium Stearate Silicon Dioxide Microcrystalline Cellulose Vegetable Hypromellose Water, Purified
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use: Adults: Take 1 capsule daily with a glass of water or juice or as directed by your healthcare practitioner.

Warnings & Precautions

Do not use if seal is broken.

Keep out of reach of children.

Formulation Notes

B6 SAP helps replenish depleted vitamin B6 stores and supports cardiovascular health, homocysteine metabolism, hemoglobin formation, neurotransmitter synthesis, and antioxidant status.

B6 SAP contains the activated enzyme form pyridoxal-5'-phosphate, in a blend of B vitamins, choline and biotin to support optimal B6 metabolism.

All ingredients listed for this product lot number have been tested by a third-party laboratory for identity, potency, and purity.

Contains no: Gluten, soy, wheat, corn, eggs, dairy, yeast, citrus, preservatives, artificial flavor or color, starch, or sugar.

This product is non-GMO and vegan friendly.

This product is non-GMO and vegan friendly.

Color, size and smell may vary from one lot to another.

Vitamin B6

Made in Canada

Additional Information

This product is very sensitive to heat and humidity Store in a cool and dry place. Do not remove silica pack. Ensure lid is closed properly after each use.

NPN 80045616

Metadata

Product Details

UPC / SKU8 56711 00132 0
DSLD Entry Date2022-09-22
Product TypeOther Combinations
FormCapsule
BrandNFH
DSLD ID272998
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
Compare

Similar Products

Bio-Cetin Forte
Douglas Laboratories · Capsule
100
Benfotiamine-V 150 mg
Benfotiamine.Net · Capsule
100
Vitamin B1 250 mg
The Vitamin Shoppe · Capsule
100
Vitamin B1 250 mg
The Vitamin Shoppe · Capsule
100
Vitamin B1 (Thiamin) 100 mg
Solgar · Capsule
100
View all Thiamine products →
Thiamine research Best Thiamine All Thiamine products More from NFH View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.