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Immune Defense Packets Mixed Berry

product on market Powder Culturelle Safety: 97/100
97/100

This product looks safe

  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 58% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C, thiamine, and riboflavin are essential nutrients that support immune function and cellular energy metabolism. There is strong research evidence supporting the roles of these vitamins in maintaining overall health. The product maintains a high safety profile based on the provided scoring.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Immune Defense Packets Mixed Berry
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Packet(s)
Serving Size
20
Servings
Other Combinations
Product Type
58%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
90 mg (100% DV)
1.2 mg (100% DV)
Within RDA (1.0× RDA) 76 studies (A:0, B:33)
1.3 mg (100% DV)
Within RDA (1.0× RDA) 13 studies (A:0, B:1)
5.6 mg (35% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
1.7 mg (100% DV)
1.3× RDA — within safe limits 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
2.4 mcg (100% DV)
Within RDA (1.0× RDA) 139 studies (A:1, B:44)
5 mg (100% DV)
Within RDA (1.0× RDA) 2 studies — no high-quality reviews
Sodium
5 mg (1% DV)
Market median: 80.0mg (20 products) 337 studies (A:8, B:183)

Other Ingredients

Fructooligosaccharides Citric Acid Malic Acid Vegetable juice Natural & Artificial flavor Sucralose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Once daily

Directions for 12 years of age and older: For daily use, take one (1) single serve packet per day. Simply mix one packet with 8 or more ounces of water and enjoy. More water equals lighter flavor. For optimal results, continued daily use is suggested.

Warnings & Precautions

Tamper Evident: Product is sealed within packets. Do not use if any part of the packet is torn, open or damaged. When first taking Culturelle, you may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms persist after two weeks.

For questions, concerns or to report an adverse event, please call (800) 722-3476.

Not a reduced calorie food.

Keep out of reach of children.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition.

Formulation Notes

Unlike ordinary immune health products, Culturelle Immune Defense Packets have a breakthrough formula that easily transforms your water into an infusion of immune & energy supporting hydration.

70% Lactobacillus rhamnosus GG Probiotic Contains the power of probiotics which work in your digestive tract where 70% of your immune system resides. With 10 billion CFUs of scientifically studied Lactobacillus rhamnosus GG, it helps balance your immune responses by working in your body’s microbiome. B vitamins Vitamin C boost Vitamin C & B Vitamins Plus, a specially formulated blend of vitamin C & energy-inducing B vitamins to deliver extra immune support and sustained energy levels.

Immune Support Formula Together, they work naturally with your body to help keep you feeling your best and your immune system going strong all day long.

Immune support formula

Probiotics Vitamin C & B vitamins

Based on the number of Lactobacillus rhamnosus GG clinical studies, as of January 2021. B vitamins support energy through metabolic function.

Guaranteed potency through date on box when stored as directed.

Meets the FDA’s guidelines for gluten-free.

Most clinically researched strain in the world Guaranteed purity & potency

Dairy - Gluten - Soy - Free

Probiotic + vitamin C & B vitamins

Probiotics 24 hour immune support Helps support your natural immune defenses Promotes all-day energy

Mixed berry Natural & artificial flavors Flavored packets

Allergy friendly

Free from Milk - Wheat - Eggs Tree Nuts - Peanuts

Additional Information

Trust Your Gut Daily to Culturelle

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

Our brand values We’re on a mission to inspire better health & wellness for you & your family. We believe in integrity, so we hold ourselves to the highest standards of truth. We believe in the natural power of your body’s microbiome, & in scientific research & products that will unlock its full potential. We believe in uncompromising quality, safety & proven efficacy. We believe in empowering you to embrace every day with confidence.

With the #1 clinically studied probiotic

Metadata

Product Details

UPC / SKU0 49100 40078 5
DSLD Entry Date2022-06-16
Product TypeOther Combinations
FormPowder
DSLD ID267566
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.