🟢 92/100

This product looks safe

  • Niacin: 353mg is 10.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 555mg is 555.0× the Tolerable Upper Intake Level (1.0mg)
  • 90% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 353mg is 10.1× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 555mg is 555.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size
90 Servings
Other Combinations Product Type
90% Evidence Coverage

Supplement Facts — Evidence Check

100 mg (8333% DV)
📊 83.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 100mg
7.5 mg (577% DV)
📊 5.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 7.5mg
353 mg (2206% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 10.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 353mg UL 35mg
100 mg (5882% DV)
📊 76.9× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 100mg UL 100mg
555 mcg DFE (139% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 555.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 555mg UL 1.0mg
1000 mcg (41667% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg
500 mcg (1667% DV)
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg
300 mg (6000% DV)
📊 60.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 300mg
240 mg (44% DV)
✅ Within RDA (0.4× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 240mg UL 3500mg
393 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 393mg

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Capsule Silicon Dioxide Hydroxypropyl Cellulose Sodium Stearyl Fumarate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 1 capsule 1-3 time daily with food, or as directed by a qualified health care practitioner.

⚠️ Warnings & Precautions

Do not use if safety seal is broken.

Warning: Consult your physician before use if you are pregnant, lactating, have a medical condition, or if you're taking any medication.

Keep out of reach of children.

To report a serious adverse event or obtain product information, call 1-866-215-0450

🧪 Formulation Notes

GMP Manufacturing Quality assured Independent testing

Discussion: Advanced B Complex was designed to provide the most advanced forms of B vitamins in the most scientifically discerning ratios available. Advanced B Complex contains benfotiamine, a form of vitamin B1 that is more bioavailable than other forms of thiamin, as well as pyridoxal-5'phosphate (P5P), methylcobalamin and L-5-methyltetrahydrofolate, bioactive forms of vitamin B6, B12 and folate respectively.

Biologically active full-spectrum B-complex

Vegan

Non-GMO Gluten Free

AOR guarantees that all ingredients have been declared on the label.

Made without wheat, gluten, nuts, peanuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

Product of Canada

Additional Information

Store tightly sealed in a cool, dry place.

Product Details

UPC / SKU 6 24917 08167 1
DSLD Entry Date 2022-05-19
Product Type Other Combinations
Form Capsule
DSLD ID 263431
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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