🟢 96/100

This product looks safe

  • Niacin: 200mg is 5.7× the Tolerable Upper Intake Level (35mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 200mg is 5.7× the Tolerable Upper Intake Level (35mg)

Label Data

2 Softgel(s) Serving Size
50 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
15 mg (1000% DV)
📊 12.5× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 15mg
17 mg (1000% DV)
📊 13.1× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 17mg
200 mg (1000% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 5.7× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 200mg UL 35mg
20 mg (1000% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
60 mcg (1000% DV)
📊 25.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.06mg
100 mg (1000% DV)
📊 20.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 100mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 0.6mg UL 20mg

Other Ingredients

Thiamine Mononitrate Niacinamide Pyridoxine Hydrochloride Cyanocobalamin Calcium Pantothenate Para-Aminobenzoic Acid Soybean Oil Gelatin Glycerin Soy Lecithin Caramel color Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take two (2) softgels daily, preferably with a meal.

⚠️ Warnings & Precautions

Contains soy ingredients.

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

🧪 Formulation Notes

Supports Energy Metabolism and Nervous System Health

Gluten Free

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Additional Information

Formula 705

Keep tightly closed. Store at room temperature: 59 degrees-86 degrees F (15 degrees to 30 degrees C).

Product Details

DSLD Entry Date 2021-10-22
Product Type Other Combinations
Form Softgel Capsule
DSLD ID 260381
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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