🟢 97/100

This product looks safe

  • Folate: 40mg is 40.0× the Tolerable Upper Intake Level (1.0mg)
  • 75% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 40mg is 40.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Botanical with Nutrients Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

1.2 mg (100% DV)
✅ Within RDA (1.0× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 1.2mg
1.3 mg (100% DV)
✅ Within RDA (1.0× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 1.3mg
4 mg (25% DV)
✅ Within RDA (0.3× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 4mg UL 35mg
1.7 mg (100% DV)
✅ 1.3× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 1.7mg UL 100mg
40 mcg DFE (10% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 40.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 40mg UL 1.0mg
2.4 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.0024 mg) 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.0024mg
30 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.03mg
5 mg (100% DV)
✅ Within RDA (1.0× RDA of 5 mg) 📚 1 studies — no high-quality reviews
RDA 5mg This product: 5mg
105 mg (25% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 105mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 50mg UL 1200mg
Organic Herbal Blend
300 mg
Organic Fruit and Vegetable Blend
50 mg

Other Ingredients

organic Rice Flour Hypromellose L-Leucine organic Rice hull concentrate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Adults: Take two (2) capsules daily with food. Do not exceed suggested use. Not formulated for use in children.

⚠️ Warnings & Precautions

Do not exceed suggested use.

Not formulated for use in children.

As with any supplement, if you are pregnant, nursing, or taking medication, consult your doctor before use. If you are taking medications, including blood thinners or antidepressants, consult your doctor before use. Ginseng can enhance the action of psychostimulant drugs.

Ginseng can enhance the action of psychostimulant drugs.

Do not consume if pregnant or nursing

Keep out of reach of children.

If taking other supplements, read label, since supplements may contain the same ingredient.

Bottle sealed with printed foil under cap. Do not use if foil is torn.

🧪 Formulation Notes

Whole food benefit blend CoQ10 & B-vitamins

CoQ10 and B-vitamins help support daily energy needs

Additional Information

Store at room temperature. Protect from heat, light, and moisture. Keep bottle tightly closed.

Questions? Comments? Call 1-877-CENTRUM (236-8786) For most recent product information, visit www.centrum.com

Product Details

UPC / SKU 3 0005 4471 60 4
DSLD Entry Date 2021-11-19
Product Type Botanical with Nutrients
Form Capsule
Brand Centrum
DSLD ID 256981
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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