Knee, Hip & Joint Complex

product on market Capsule SigmaCeutical 🟢 Safety: 100/100
Brand: SigmaCeutical
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

Label for Knee, Hip & Joint Complex
📄 Open Full PDF View on NIH DSLD →
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Label Data

1 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Cetyl Myristoleate 20% Complex
100 mg
2.5 mg
📊 Market median: 100.0mg (173 products)
Median 100.0mg This product: 2.5mg
MSM
100 mg
📊 Market median: 1000.0mg (2 products)
This product: 100mg
125 mg
📊 Market median: 500.0mg (138 products) 📚 2 studies — no high-quality reviews
This product: 125mg
50 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 50mg
50 mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 50mg
50 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 50mg
50 mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 50mg
50 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 50mg
Skullcap 4:1 extract
25 mg
2.5 mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 2.5mg
2.5 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 2.5mg

Other Ingredients

Gelatin Rice powder Vegetable Magnesium Stearate Silicon Dioxide

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (17% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: 1 capsule taken 1 to 2 times daily preferably with meals or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Supports comfort and flexibility

With CMO, turmeric & MSM

Additional Information

Store in a cool, dry place.

Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured Made In USA

Please go to www.sigmaceutical.com for special discounts & offers! SigmaCeutical The sum of all health

Product Details

UPC / SKU B0731QF7Y4
DSLD Entry Date 2021-11-19
Product Type Other Combinations
Form Capsule
Brand SigmaCeutical
DSLD ID 255964
Data Updated 2026-04-11

Research Evidence

14 Research Sources
50 Avg Quality Score
9 Rct
3 Clinical Trial
1 Systematic Review
1 Guideline
B Dressings and topical agents containing hyaluronic acid for chronic wound healing
Systematic Review The Cochrane database of systematic reviews 2023
PubMed DOI
B Effect of laughter exercise versus 0.1% sodium hyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial
Rct BMJ (Clinical research ed.) 2024
PubMed DOI
B Expert consensus on hyaluronic acid injections for knee osteoarthritis: a patient-centered approach.
Guideline Aging clinical and experimental research 2026
PubMed DOI
C The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial
Rct Nutrients 2024
PubMed DOI
C Effects of ozone combined with articular injection of sodium hyaluronate on patients with knee osteoarthritis and their inflammatory factors and hemorheological indices.
Rct African health sciences
PubMed DOI
C The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain: An 8-week randomized double-blind placebo-controlled trial.
Rct Medicine
PubMed DOI
C Liquid combination of hyaluronan, glucosamine, and chondroitin as a dietary supplement for knee osteoarthritis patients with moderate knee pain: A randomized controlled study.
Rct Medicine
PubMed DOI
C Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial.
Rct The journal of sexual medicine
PubMed DOI
C PMCF Study to Evaluate Performance and Safety of 'Hyaluronic Acid (HA)-Based Eyedrops' Used to Relieve Dry Eye Symptoms
Clinical Trial ClinicalTrials.gov 2022
ClinicalTrials.gov
C Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections
Clinical Trial ClinicalTrials.gov 2022
ClinicalTrials.gov
View all evidence for Hyaluronic Acid →

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